Clinical Pharmacology and Toxicology, Department of General Internal Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Institute of Pharmacology, University of Bern, Bern, Switzerland.
PLoS One. 2018 Mar 29;13(3):e0195234. doi: 10.1371/journal.pone.0195234. eCollection 2018.
Psychoactive substances are often regarded as causal factors contributing to violent injuries, sexual abuse and homicides. While these effects have been demonstrated for some substances (e.g. cocaine), current available data for others are more controversial (e.g. cannabis) or very limited (e.g. ecstasy).
To collect data on the type and frequency of psychoactive substance use in cases of emergency department (ED) presentations related to interpersonal violence.
Retrospective study at the University Hospital of Bern, Switzerland, between May 2012 and June 2016. The study covered cases of violent crime associated with psychoactive substances. Cases of isolated ethanol intoxication, suicide attempts, and substance use for medical purposes were excluded.
The study included 103 cases among the 164,846 ED attendances. In the majority of the cases, the type of violence was bodily force (52%) related to urban violence (83%). The mean patient age was 29 years and 79% were male. 63% of the patients reported use of more than one drug; alcohol co-use was reported in 60% of the cases. Besides alcohol, the substances most often reported were cannabis (50%) and cocaine (21%). Alcohol and cannabis was also the most commonly reported substance combination (36% of the total cases). Urine drug screening was performed in 34% of the cases and cannabis and cocaine were the most commonly detected substances (46% and 19%, respectively). There were no cases of novel substances. 23% of the patients were admitted to a hospital ward, 10% to a psychiatric clinic.
Cannabis and cocaine were, besides alcohol, the substances most often reported in ED presentations related to offences of violence. Because of the high prevalence of alcohol co-use, no final conclusions can be drawn on the contribution of single substances.
精神活性物质常被视为导致暴力伤害、性虐待和凶杀的原因。虽然一些物质(如可卡因)的这些影响已经得到证实,但其他物质(如大麻)的现有数据存在争议,而其他物质(如摇头丸)的数据则非常有限。
收集与人际暴力相关的急诊科就诊中精神活性物质使用的类型和频率数据。
瑞士伯尔尼大学医院的回顾性研究,时间为 2012 年 5 月至 2016 年 6 月。研究涵盖与精神活性物质有关的暴力犯罪病例。排除了孤立的乙醇中毒、自杀企图和出于医疗目的的物质使用病例。
在 164846 例急诊科就诊中,有 103 例符合研究条件。在大多数情况下,暴力类型是与城市暴力(83%)有关的身体暴力(52%)。患者平均年龄为 29 岁,79%为男性。63%的患者报告使用了一种以上的药物;60%的病例报告同时使用酒精。除酒精外,最常报告的物质是大麻(50%)和可卡因(21%)。酒精和大麻也是最常报告的物质组合(占总病例的 36%)。在 34%的病例中进行了尿液药物筛查,最常检测到的物质是大麻和可卡因(分别为 46%和 19%)。没有新型物质的病例。23%的患者被收治到病房,10%的患者被收治到精神科诊所。
除酒精外,在与暴力犯罪相关的急诊科就诊中,最常报告的物质是大麻和可卡因。由于酒精共同使用的高患病率,不能对单一物质的作用得出最终结论。