Virgilio Edoardo, Balducci Genoveffa, Mercantini Paolo, Giarnieri Enrico, Giovagnoli Maria Rosaria, Montagnini Monica, Proietti Antonella, D'Urso Rosaria, Cavallini Marco
Department of Medical and Surgical Sciences and Translational Medicine, Faculty of Medicine and Psychology, Sapienza University, St. Andrea Hospital, Rome, Italy
Department of Medical and Surgical Sciences and Translational Medicine, Faculty of Medicine and Psychology, Sapienza University, St. Andrea Hospital, Rome, Italy.
Anticancer Res. 2018 Apr;38(4):1911-1916. doi: 10.21873/anticanres.12428.
BACKGROUND/AIM: Although there is an increasing number of studies on laparoscopic resection of early gastric cancer (EGC), as of 2018 no standardized strategy exists. We reviewed available literature dealing with laparoscopic intragastric (intraluminal) surgery (LIGS) conducted for patients with EGC to better define indications, benefits and limitations of this particular minimally invasive technique.
PubMed, MEDLINE, Science Direct, Scopus, Web of Science, Google Scholar and ResearchGate were the search engines investigated. Only LIGS for EGC was entertained; studies conducted for other gastric diseases were excluded. Suitable articles written in all languages were included in the review.
As of 2018, we found 19 studies dealing with LIGS for EGC: studies on 72 humans and four pigs were identified. Among 72 human participants, there were 59 mucosal, five submucosal and one subserosal cancer.
Based on our review, LIGS appears as a cogent option to endoscopic resection for treating superficial EGC.
背景/目的：尽管关于早期胃癌（EGC）腹腔镜切除术的研究越来越多，但截至2018年，尚无标准化策略。我们回顾了有关为EGC患者进行腹腔镜胃内（腔内）手术（LIGS）的现有文献，以更好地界定这种特殊微创技术的适应证、益处和局限性。
检索了PubMed、MEDLINE、科学Direct、Scopus、科学网、谷歌学术和ResearchGate等搜索引擎。仅纳入了关于EGC的LIGS研究；排除了针对其他胃部疾病的研究。综述纳入了所有语言撰写且合适的文章。
截至2018年，我们发现了19项关于EGC的LIGS研究：确定了72例人体研究和4例猪研究。在72名人类参与者中，有59例黏膜癌、5例黏膜下癌和1例浆膜下癌。
基于我们的综述，LIGS似乎是治疗浅表性EGC的一种有力的内镜切除替代方案。
