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双重抗血小板治疗对拔牙后出血影响的临床评估

Clinical Evaluation of Role of Dual Antiplatelet Therapy on Bleeding after Dental Extraction.

作者信息

Babaji Prashant, Rishal Yousef

机构信息

Department of Pedodontics, Sharavathi Dental College, Shimoga, Karnataka, India.

Department of Conservative Dentistry and Endodontics, Malabar Dental College and Research Centre, Edappal, Kerala, India.

出版信息

Contemp Clin Dent. 2018 Jan-Mar;9(1):41-44. doi: 10.4103/ccd.ccd_702_17.

Abstract

AIMS AND OBJECTIVES

Altered platelet function and increased bleeding time (BT) can occur with antiplatelet therapy. This study was conducted to evaluate the need for stoppage of dual antiplatelet therapy in patients undergoing dental extractions.

MATERIALS AND METHODS

One hundred and fifty patients indicated for dental extraction were grouped as Group I: Consisted of 75 patients on dual antiplatelet therapy and Group II: Consisted of 75 patients who have discontinued antiplatelet therapy 1 week before dental extraction. BT of all the participants was recorded before extraction procedures. Under local anesthesia, single molar tooth indicated for simple extraction was done in both the groups. Suturing along with pressure pack was done after extraction. BT after extraction was statistically checked between the groups after 1 h and 24 h using Chi-square test with < 0.05.

RESULTS

Postoperatively, none of the patients in both the groups showed active bleeding 1 h and 24 h. No bleeding was seen in 73 patients in Group I and 78 patients in Group II after 24 h.

CONCLUSION

This study concluded that there is no significant difference in BT in both the groups. Antiplatelet monotherapy or even antiplatelet dual therapy needs no alteration or stopped before minor oral surgical procedures. Most of the postoperative bleeding can be easily controlled by local hemostatic measures.

摘要

目的与目标

抗血小板治疗可能会改变血小板功能并延长出血时间(BT)。本研究旨在评估接受拔牙的患者停用双联抗血小板治疗的必要性。

材料与方法

150例拟行拔牙的患者被分为两组:第一组75例,正在接受双联抗血小板治疗;第二组75例,在拔牙前1周已停用抗血小板治疗。在拔牙前记录所有参与者的出血时间。两组均在局部麻醉下拔除一颗单颗磨牙,拔牙后进行缝合并加压包扎。拔牙后1小时和24小时,采用卡方检验对两组的出血时间进行统计学检查,显著性水平为<0.05。

结果

术后,两组患者在1小时和24小时均未出现活动性出血。24小时后,第一组73例患者和第二组78例患者均未出现出血。

结论

本研究得出结论,两组的出血时间无显著差异。在小型口腔外科手术前,无需改变或停用抗血小板单药治疗甚至双联抗血小板治疗。大多数术后出血可通过局部止血措施轻松控制。

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