Mayo Clinic, Scottsdale, Arizona, USA.
Curr Opin Neurol. 2018 Jun;31(3):268-273. doi: 10.1097/WCO.0000000000000557.
The purpose of this narrative review is to provide an overview of the currently available noninvasive neuromodulation devices for the treatment of migraine and cluster headache.
Over the last decade, several noninvasive devices have undergone development and clinical trials to evaluate efficacy and safety. Based on this body of work, single-pulse transcranial magnetic stimulation, transcutaneous supraorbital neurostimulation, and noninvasive vagal nerve stimulation devices have been cleared by the United States Food and Drug Administration and are available for clinical use for the treatment of primary headache disorders.
Overall, these novel noninvasive devices appear to be safe, well tolerated, and have demonstrated promising results in clinical trials in both migraine and cluster headache. This narrative review will provide a summary and update of the proposed mechanisms of action, evidence, safety, and future directions of various currently available modalities of noninvasive neuromodulation for the treatment of migraine and cluster headache.
本文旨在概述目前可用于治疗偏头痛和丛集性头痛的非侵入性神经调节设备。
在过去十年中，已经开发并进行了多项临床试验，以评估多种非侵入性设备的疗效和安全性。基于这些研究，单脉冲经颅磁刺激、眶上经皮神经刺激和非侵入性迷走神经刺激设备已获得美国食品和药物管理局（FDA）批准，可用于治疗原发性头痛障碍。
总的来说，这些新型非侵入性设备似乎安全、耐受良好，并且在偏头痛和丛集性头痛的临床试验中显示出有希望的结果。本文将综述目前可用于治疗偏头痛和丛集性头痛的各种非侵入性神经调节方式的作用机制、证据、安全性和未来方向。
