新生儿及小婴儿的结合胆红素血症

Conjugated Hyperbilirubinemia in the Neonate and Young Infant.

作者信息

Weiss Anna K, Vora Parag V

机构信息

Assistant Professor of Clinical Pediatrics (Weiss), Perelman School of Medicine at the University of Pennsylvania; Attending Physician (Weiss), Division of Emergency Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA; and Attending Physician (Vora), Pediatric Emergency Medicine, Envision Physician Services, Capital Health Medical Center, Pennington, NJ.

出版信息

Pediatr Emerg Care. 2018 Apr;34(4):280-283. doi: 10.1097/PEC.0000000000001467.

DOI:10.1097/PEC.0000000000001467

PMID:29601463

Abstract

Cholestatic jaundice in the first few weeks of life may herald potentially life-threatening pathology. It is therefore incumbent upon the pediatric practitioner to have a high index of suspicion for severe disease when investigating jaundice in a young infant. This article outlines the epidemiology, pathophysiology, differential diagnosis, and diagnostic workup for both the most common and the most severe causes of cholestasis in the neonatal period.

摘要

出生后最初几周出现的胆汁淤积性黄疸可能预示着潜在的危及生命的病变。因此，在对幼儿黄疸进行调查时，儿科医生有责任对严重疾病保持高度怀疑。本文概述了新生儿期胆汁淤积最常见和最严重病因的流行病学、病理生理学、鉴别诊断及诊断检查。