依恋取向与冠心病患者抑郁病程的关系:SPIRR-CAD 试验的二次分析。
The relationship between attachment orientations and the course of depression in coronary artery disease patients: A secondary analysis of the SPIRR-CAD trial.
机构信息
Dept. of Psychosomatic Medicine and Psychotherapy, Paracelsus Medical University, Nuremberg General Hospital, Germany.
Dept. of Psychosomatic Medicine and Psychotherapy, Paracelsus Medical University, Nuremberg General Hospital, Germany.
出版信息
J Psychosom Res. 2018 May;108:39-46. doi: 10.1016/j.jpsychores.2018.02.014. Epub 2018 Feb 24.
OBJECTIVE
The relationship between attachment orientations and the recovery from depressive symptoms in patients diagnosed with coronary artery disease (CAD) with and without a psychotherapeutic intervention was examined in this study.
METHODS
In a multicenter trial of 570 depressed CAD patients (SPIRR-CAD), assigned to usual care plus either a stepwise psychotherapy intervention or one information session, 522 patients provided attachment data at baseline. Attachment was measured with the Relationship Scales Questionnaire (RSQ), yielding four attachment orientations. The primary outcome was change in Hospital Anxiety and Depression Scale depression (HADS-D) scores from baseline to follow-up at 18 months. Secondary outcomes were HADS-D scores at 1, 6, 12, and 24 months.
RESULTS
Independent of treatment assignment, attachment was related to change in depression at 18 months (p < 0.01) with secure attachment resulting in a significant reduction (-2.72, SE = 0.27) in depression compared to dismissive-avoidant (-1.51, SE = 0.35, p = 0.040) and fearful-avoidant (-0.65, SE = 0.61, p = 0.012) attachment. Patients with anxious-preoccupied attachment showed changes similar to secure attachment (-2.01, SE = 0.47). An explorative subgroup analysis across all assessment time points revealed patients with a dismissive-avoidant attachment benefitted from psychotherapy (average mean difference = 0.93, SE = 0.47, p = 0.048).
CONCLUSION
Attachment played an important role for improvement in depressive symptoms. Only dismissive-avoidant patients seemed to benefit from the intervention. The lack of improvement in fearful-avoidant patients shows a need for specific interventions for this group.
TRIAL REGISTRATION
www.clinicaltrials.govNCT00705965; www.isrctn.com ISRCTN76240576.
目的
本研究旨在探讨在接受冠状动脉疾病(CAD)治疗且未接受心理治疗的患者中,依恋取向与抑郁症状恢复之间的关系。
方法
在一项对 570 例抑郁 CAD 患者(SPIRR-CAD)的多中心试验中,患者被随机分配至常规治疗加逐步心理治疗干预或一次信息会议。在基线时,522 例患者提供了依恋数据。依恋通过关系量表问卷(RSQ)进行测量,得出四个依恋取向。主要结局是从基线到 18 个月时的医院焦虑和抑郁量表抑郁(HADS-D)评分的变化。次要结局是 1、6、12 和 24 个月时的 HADS-D 评分。
结果
独立于治疗分配,依恋与 18 个月时的抑郁变化相关(p<0.01),与回避型(-1.51,SE=0.35,p=0.040)和恐惧型(-0.65,SE=0.61,p=0.012)依恋相比,安全型依恋导致抑郁显著降低(-2.72,SE=0.27)。具有焦虑依恋的患者变化与安全型依恋相似(-2.01,SE=0.47)。在所有评估时间点的探索性亚组分析中,发现回避型依恋患者受益于心理治疗(平均平均差异=0.93,SE=0.47,p=0.048)。
结论
依恋对改善抑郁症状起着重要作用。只有回避型患者似乎从干预中受益。恐惧型患者没有改善表明需要针对该群体进行特定干预。
试验注册
www.clinicaltrials.govNCT00705965;www.isrctn.com ISRCTN76240576。