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1
Oversized galactosides as a probe for conformational dynamics in LacY.
Proc Natl Acad Sci U S A. 2018 Apr 17;115(16):4146-4151. doi: 10.1073/pnas.1800706115. Epub 2018 Mar 30.
2
Outward-facing conformers of LacY stabilized by nanobodies.
Proc Natl Acad Sci U S A. 2014 Dec 30;111(52):18548-53. doi: 10.1073/pnas.1422265112. Epub 2014 Dec 15.
3
Crystal structure of a LacY-nanobody complex in a periplasmic-open conformation.
Proc Natl Acad Sci U S A. 2016 Nov 1;113(44):12420-12425. doi: 10.1073/pnas.1615414113. Epub 2016 Oct 19.
4
Engineered occluded apo-intermediate of LacY.
Proc Natl Acad Sci U S A. 2018 Dec 11;115(50):12716-12721. doi: 10.1073/pnas.1816267115. Epub 2018 Nov 26.
5
Real-time conformational changes in LacY.
Proc Natl Acad Sci U S A. 2014 Jun 10;111(23):8440-5. doi: 10.1073/pnas.1408374111. Epub 2014 May 28.
6
Opening the periplasmic cavity in lactose permease is the limiting step for sugar binding.
Proc Natl Acad Sci U S A. 2011 Sep 13;108(37):15147-51. doi: 10.1073/pnas.1112157108. Epub 2011 Sep 6.
7
Diversity in kinetics correlated with structure in nano body-stabilized LacY.
PLoS One. 2020 May 7;15(5):e0232846. doi: 10.1371/journal.pone.0232846. eCollection 2020.
8
Direct sugar binding to LacY measured by resonance energy transfer.
Biochemistry. 2006 Dec 26;45(51):15279-87. doi: 10.1021/bi061632m. Epub 2006 Nov 29.
9
Lactose permease and the alternating access mechanism.
Biochemistry. 2011 Nov 15;50(45):9684-93. doi: 10.1021/bi2014294. Epub 2011 Oct 19.
10
An Asymmetric Conformational Change in LacY.
Biochemistry. 2017 Apr 4;56(13):1943-1950. doi: 10.1021/acs.biochem.7b00134. Epub 2017 Mar 23.

引用本文的文献

1
Function Trumps Form in Two Sugar Symporters, and .
Int J Mol Sci. 2021 Mar 30;22(7):3572. doi: 10.3390/ijms22073572.
2
Directed evolution of an α1,3-fucosyltransferase using a single-cell ultrahigh-throughput screening method.
Sci Adv. 2019 Oct 9;5(10):eaaw8451. doi: 10.1126/sciadv.aaw8451. eCollection 2019 Oct.
3
It takes two to tango: The dance of the permease.
J Gen Physiol. 2019 Jul 1;151(7):878-886. doi: 10.1085/jgp.201912377. Epub 2019 May 30.
4
Engineered occluded apo-intermediate of LacY.
Proc Natl Acad Sci U S A. 2018 Dec 11;115(50):12716-12721. doi: 10.1073/pnas.1816267115. Epub 2018 Nov 26.

本文引用的文献

1
An Asymmetric Conformational Change in LacY.
Biochemistry. 2017 Apr 4;56(13):1943-1950. doi: 10.1021/acs.biochem.7b00134. Epub 2017 Mar 23.
2
Crystal structure of a LacY-nanobody complex in a periplasmic-open conformation.
Proc Natl Acad Sci U S A. 2016 Nov 1;113(44):12420-12425. doi: 10.1073/pnas.1615414113. Epub 2016 Oct 19.
4
Structure of LacY with an α-substituted galactoside: Connecting the binding site to the protonation site.
Proc Natl Acad Sci U S A. 2015 Jul 21;112(29):9004-9. doi: 10.1073/pnas.1509854112. Epub 2015 Jul 8.
5
A chemiosmotic mechanism of symport.
Proc Natl Acad Sci U S A. 2015 Feb 3;112(5):1259-64. doi: 10.1073/pnas.1419325112. Epub 2015 Jan 7.
6
Outward-facing conformers of LacY stabilized by nanobodies.
Proc Natl Acad Sci U S A. 2014 Dec 30;111(52):18548-53. doi: 10.1073/pnas.1422265112. Epub 2014 Dec 15.
7
Tackling vancomycin-resistant bacteria with 'lipophilic-vancomycin-carbohydrate conjugates'.
J Antibiot (Tokyo). 2015 May;68(5):302-12. doi: 10.1038/ja.2014.144. Epub 2014 Oct 29.
8
Real-time conformational changes in LacY.
Proc Natl Acad Sci U S A. 2014 Jun 10;111(23):8440-5. doi: 10.1073/pnas.1408374111. Epub 2014 May 28.
9
Structure of sugar-bound LacY.
Proc Natl Acad Sci U S A. 2014 Feb 4;111(5):1784-8. doi: 10.1073/pnas.1324141111. Epub 2014 Jan 22.
10
The periplasmic cavity of LacY mutant Cys154→Gly: how open is open?
Biochemistry. 2013 Sep 17;52(37):6568-74. doi: 10.1021/bi401026d. Epub 2013 Aug 30.

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