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睾丸癌的治疗机会和区域化服务差距。

Disparities in Access and Regionalization of Care in Testicular Cancer.

机构信息

Department of Urology, University of Washington School of Medicine, Seattle, WA.

Department of Urology, University of Washington School of Medicine, Seattle, WA.

出版信息

Clin Genitourin Cancer. 2018 Aug;16(4):e785-e793. doi: 10.1016/j.clgc.2018.02.014. Epub 2018 Feb 23.


DOI:10.1016/j.clgc.2018.02.014
PMID:29605587
Abstract

INTRODUCTION: Timely mobilization of specialized resources are needed to achieve optimal outcomes in testicular cancer. We used the National Cancer Database to investigate the hospital and demographic features driving disparity. PATIENTS AND METHODS: We identified adult men with testicular tumors diagnosed from 2004 to 2013. We a priori examined the association among race/ethnicity, socioeconomic status (SES), travel burden, hospital characteristics, and indicators of delays in testicular cancer care. The outcomes included large primary tumor, stage III at diagnosis, orchiectomy delay, and mortality. The analyses included multivariable Cox proportional hazards regression for time-dependent outcomes and logistic regression for categorical outcomes. RESULTS: Of 31,964 men, 29% had a large primary tumor, 17% presented with stage III disease, 10% experienced an orchiectomy delay, and 6% died. Black race or Hispanic ethnicity, low SES, and underinsurance were associated with poorer outcomes (P < .001 for all). Higher hospital volume, cancer center status, and lower travel burden were associated with improved outcomes (P < .001 for all). CONCLUSION: Nonwhite race/ethnicity, low SES, and underinsurance were associated with diminished access to testicular cancer care. Insurance status, a marker of SES, had the most consistent association with poor outcomes. This finding highlights the oncologic imperative to improve access to adequate health insurance. Regionalization of subspecialty care might, paradoxically, improve outcomes but also create additional barriers in the form of an added travel burden.

摘要

简介:为了在睾丸癌治疗中取得最佳效果,需要及时调动专业资源。我们利用国家癌症数据库,研究导致这种差异的医院和人口统计学特征。

患者和方法:我们确定了 2004 年至 2013 年间被诊断患有睾丸肿瘤的成年男性患者。我们预先研究了种族/民族、社会经济地位(SES)、旅行负担、医院特征以及睾丸癌治疗延迟指标之间的关联。结果包括原发肿瘤较大、诊断时为 III 期、睾丸切除术延迟和死亡率。分析包括多变量 Cox 比例风险回归用于时间依赖性结果和逻辑回归用于分类结果。

结果:在 31964 名男性中,29%的患者原发肿瘤较大,17%的患者诊断为 III 期疾病,10%的患者经历了睾丸切除术延迟,6%的患者死亡。黑人或西班牙裔、低 SES 和未参保与较差的结果相关(所有 P<0.001)。较高的医院容量、癌症中心地位和较低的旅行负担与改善的结果相关(所有 P<0.001)。

结论:非白种人/族裔、低 SES 和未参保与睾丸癌治疗机会减少有关。保险状况,SES 的标志,与不良结果的关联最一致。这一发现突出了改善获得充足健康保险的肿瘤学必要性。专科医疗资源的区域化可能会改善结果,但也会以额外的旅行负担的形式产生额外的障碍。

相似文献

[1]
Disparities in Access and Regionalization of Care in Testicular Cancer.

Clin Genitourin Cancer. 2018-2-23

[2]
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[3]
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[4]
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[5]
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[6]
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[8]
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Am J Obstet Gynecol. 2015-4

[9]
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[10]
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引用本文的文献

[1]
Disparities in Testicular Cancer: A Review of the Literature.

Cancers (Basel). 2024-10-10

[2]
The prognostic impact of treatment centralization in patients with testicular germ cell tumors: analysis of hospital-based cancer registry data in Japan.

Int J Clin Oncol. 2024-3

[3]
Humor-Based Messaging in Testicular Cancer Awareness Campaigns: A Comparative Critical Review.

Am J Mens Health. 2023

[4]
Incidence and Survival of Testicular Cancers in a Province in Northern Italy and Their Association with Second Tumors.

Biology (Basel). 2023-11-9

[5]
Understanding Sociodemographic Factors among Hispanics Through a Population-Based Study on Testicular Cancer in Mexico.

J Racial Ethn Health Disparities. 2025-2

[6]
Impact of Cancer Care Regionalization on Patient Volume.

Ann Surg Oncol. 2023-4

[7]
Single-course bleomycin, etoposide, and cisplatin (1xBEP) as adjuvant treatment in testicular nonseminoma clinical stage 1: outcome, safety, and risk factors for relapse in a population-based study.

Ther Adv Med Oncol. 2022-3-31

[8]
A Canadian approach to the regionalization of testis cancer: A review.

Can Urol Assoc J. 2020-10

[9]
Risks from Deferring Treatment for Genitourinary Cancers: A Collaborative Review to Aid Triage and Management During the COVID-19 Pandemic.

Eur Urol. 2020-5-3

[10]
Association of hospital and surgeon volume with mortality following major surgical procedures: Meta-analysis of meta-analyses of observational studies.

Medicine (Baltimore). 2019-11

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