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睾丸癌的差异:文献综述

Disparities in Testicular Cancer: A Review of the Literature.

作者信息

Escobar Domenique, Daneshmand Siamak

机构信息

Catherine and Joseph Aresty Department of Urology, University of Southern California/Norris Comprehensive Cancer Center, University of Southern California, 1441 Eastlake Ave. NOR 7416, Los Angeles, CA 90033-9178, USA.

出版信息

Cancers (Basel). 2024 Oct 10;16(20):3433. doi: 10.3390/cancers16203433.

Abstract

: Testicular cancer is the most common malignancy diagnosed in adolescents and young adults, and evidence has emerged regarding disparities that affect different groups of patients. : In this article, we conducted a thorough review of this area and summarized the existing literature. : Some of the pertinent findings from our review include poorer outcomes for various groups including the native Māori population of New Zealand, those who live in the United States-Mexico border region, those who live in Eastern Europe, those who are uninsured and those with poorer socioeconomic status, amongst others. In the United States specifically, there is significant evidence showing that racial/ethnic minorities, compared to white patients, tend to fare worse with later presentation at higher stages and worse survival rates. Hispanic patients in particular appear to have the potential for more aggressive tumor biology than other groups and are projected to have the highest incidence rates in the US by 2026. : Overall, disparities exist in many aspects of testicular cancer and are striking in some instances, and further research is needed in this arena and in potential solutions.

摘要

睾丸癌是青少年和青年男性中最常见的恶性肿瘤,已有证据表明不同患者群体存在差异。在本文中,我们对该领域进行了全面回顾并总结了现有文献。我们回顾的一些相关发现包括,新西兰毛利原住民、居住在美国 - 墨西哥边境地区的人群、东欧人群、未参保人群以及社会经济地位较低的人群等不同群体的预后较差。特别是在美国,有大量证据表明,与白人患者相比,少数族裔/种族患者往往在疾病晚期就诊,生存率更低。尤其是西班牙裔患者,其肿瘤生物学行为似乎比其他群体更具侵袭性,预计到2026年美国其发病率将最高。总体而言,睾丸癌在许多方面存在差异,在某些情况下差异显著,该领域及潜在解决方案仍需进一步研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e31a/11505726/cac4e45c6b7c/cancers-16-03433-g001.jpg

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