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神经退行性痴呆疾病中的迈内特基底核:综述

The nucleus basalis of Meynert in neurological dementing disease: a review.

作者信息

Chozick B

出版信息

Int J Neurosci. 1987 Nov;37(1-2):31-48. doi: 10.3109/00207458708991799.

DOI:10.3109/00207458708991799
PMID:2960633
Abstract

The nucleus basalis of Meynert of the substantia innominata supplies the major cholinergic innervation of the cerebral cortex. Pathological alterations have been observed in the nucleus basalis of Meynert in several dementing neurological disorders. This paper is an overview of the work done by several researchers in their attempt to find the possible connections between pathology in the nucleus basalis of Meynert and the clinical symptomatology of dementia in several neurological diseases.

摘要

无名质的迈内特基底核为大脑皮质提供主要的胆碱能神经支配。在几种导致痴呆的神经疾病中,已观察到迈内特基底核存在病理改变。本文概述了几位研究人员的工作,他们试图找出迈内特基底核的病理与几种神经疾病中痴呆临床症状学之间的可能联系。

相似文献

1
The nucleus basalis of Meynert in neurological dementing disease: a review.神经退行性痴呆疾病中的迈内特基底核:综述
Int J Neurosci. 1987 Nov;37(1-2):31-48. doi: 10.3109/00207458708991799.
2
Note on the pathology of the basal nucleus of Meynert in degenerative brain disorders.
Schweiz Arch Neurol Neurochir Psychiatr. 1984;135(2):277-80.
3
The role of the nucleus basalis of Meynert in dementia: review and reconsideration.
Alzheimer Dis Assoc Disord. 1987;1(3):128-55. doi: 10.1097/00002093-198701030-00003.
4
The nucleus basalis of Meynert.迈内特基底核
Can J Neurol Sci. 1986 Feb;13(1):8-14. doi: 10.1017/s0317167100035721.
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The nucleus basalis of Meynert in neurological disease: a quantitative morphological study.迈内特基底核在神经疾病中的研究:一项定量形态学研究
Ann Neurol. 1985 Feb;17(2):163-70. doi: 10.1002/ana.410170210.
6
Clinical and neurochemical consequences of neuronal loss in the nucleus basalis of Meynert in Parkinson's disease and Alzheimer's disease.帕金森病和阿尔茨海默病中迈内特基底核神经元丢失的临床和神经化学后果。
Adv Neurol. 1987;45:393-7.
7
Neurone loss in the nucleus basalis of Meynert in Creutzfeldt-Jakob disease.
Acta Neuropathol. 1984;65(1):85-8. doi: 10.1007/BF00689832.
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Nucleus basalis neuronal loss, neuritic plaques and choline acetyltransferase activity in advanced Alzheimer's disease.晚期阿尔茨海默病中的基底核神经元丢失、神经炎性斑块及胆碱乙酰转移酶活性
Neuroscience. 1986 Dec;19(4):1279-91. doi: 10.1016/0306-4522(86)90142-9.
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[Abnormalities of neurotransmitters in Alzheimer's disease. Disturbance of the acetylcholine system and nucleus basalis of Meynert].
Nihon Rinsho. 1988 Jul;46(7):1491-5.
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The nucleus basalis in Huntington's disease.亨廷顿舞蹈病中的基底核。
Neurology. 1983 Oct;33(10):1262-7. doi: 10.1212/wnl.33.10.1262.

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Rapid β-amyloid deposition and cognitive impairment after cholinergic denervation in APP/PS1 mice.胆碱能神经支配缺失后 APP/PS1 小鼠中β-淀粉样蛋白的快速沉积和认知障碍。
J Neuropathol Exp Neurol. 2013 Apr;72(4):272-85. doi: 10.1097/NEN.0b013e318288a8dd.