Maucher O M, Faber M, Knipper H, Kirchner S, Schöpf E
Universitäts-Hautklinik Freiburg.
Hautarzt. 1987 Oct;38(10):577-82.
A 50-year-old female patient developed maculopapular exanthema after administration of corticoids on account of a cervical syndrome. Under topical therapy with different corticoids because of an allergic contact eczema, the skin lesions worsened and consecutive oral corticoid therapy again induced maculopapular exanthema. Skin tests revealed an eczematous contact allergy to the stereoisomeric corticoids dexamethasone and beta-methasone, as well as to two salts of these substances. Furthermore, allergies to other ingredients of the vehicles were detected. The various allergic clinical manifestations, the allergologically important corticoids, the test procedures and sensitization conditions are discussed in correlation with the literature.
一名50岁女性患者因颈椎病接受皮质类固醇治疗后出现斑丘疹性皮疹。由于过敏性接触性皮炎，在使用不同皮质类固醇进行局部治疗时，皮肤病变恶化，连续口服皮质类固醇治疗再次诱发斑丘疹性皮疹。皮肤试验显示对立体异构皮质类固醇地塞米松和倍他米松以及这两种物质的两种盐存在湿疹性接触过敏。此外，还检测到对赋形剂其他成分的过敏。结合文献讨论了各种过敏临床表现、具有过敏学意义的皮质类固醇、检测方法和致敏条件。
