Department of Food Sciences, Tabriz branch, Islamic Azad University, Tabriz, Iran; Biotechnology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Stem Cell & Regenerative Medicine Institute, Tabriz University of Medical Sciences, Tabriz, Iran.
Food Chem. 2018 Aug 1;256:156-162. doi: 10.1016/j.foodchem.2018.02.114. Epub 2018 Feb 22.
Betanin is a red food pigment with health beneficial effects. Despite interest in the use of betanin, low bioaccessibility and oxidation limit its application. To overcome these restrictions, the betanin was loaded in liposomal nanocarriers with the encapsulation efficiency of 80.35 ± 1%. To assess the efficiency of these nanocarriers, gummy candy was selected as a food model and its nutritional properties such as betanin stability and antioxidant activity were probed. The results showed that the betanin content and antioxidant activity of samples containing betanin-nanoliposomes were at least twice to those of samples containing free betanin. The tests show no differences in the sensory parameters of panelists for gummy candies fortified by betanin-loaded nanoliposomes compared to those fortified by betanin alone. As a result, the liposomal nanoparticles may be introduced as a suitable platform to stabilize and increase the bioavailability of betanin for applications in nutraceutical and medical fields.
甜菜红是一种具有健康益处的红色食品色素。尽管人们对甜菜红的应用很感兴趣,但它的生物利用度低和氧化限制了它的应用。为了克服这些限制,将甜菜红负载在脂质体纳米载体中,包封效率为 80.35±1%。为了评估这些纳米载体的效率,选择了软糖作为食品模型,并研究了其营养特性,如甜菜红的稳定性和抗氧化活性。结果表明,含有甜菜红-纳米脂质体的样品中的甜菜红含量和抗氧化活性至少是含有游离甜菜红的样品的两倍。测试结果表明,与单独添加甜菜红的软糖相比,添加负载甜菜红的纳米脂质体的软糖在感官参数方面没有差异。因此,脂质体纳米粒子可以作为一种合适的平台,用于稳定和提高甜菜红的生物利用度,应用于营养保健品和医药领域。