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一例以出血、盆腔疼痛和痛经为表现的原发性子宫淋巴瘤病例。

A Case of Primary Uterina Lymphoma Presenting with Bleeding, Pelvic Pain, and Dysmenorrhea.

作者信息

Miura Lilian Yukari, Maure Miriam Anyury Daquin, Zomer Monica Tessmann, Ribeiro Reitan, Cavalcanti Teresa Cristina Santos, Kondo William

机构信息

Vita Batel Hospital, Rua Alferes Angelo Sampaio, 1896 Curitiba, PR, Brazil.

Complejo Hospitalario Metropolitano, Via Simon Bolivar, Panama City, Panama.

出版信息

Case Rep Obstet Gynecol. 2018 Jan 22;2018:5065738. doi: 10.1155/2018/5065738. eCollection 2018.

DOI:10.1155/2018/5065738
PMID:29607236
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5828537/
Abstract

Primary non-Hodgkin's lymphoma (NHL) can arise from lymphatic cells located in solid organs (extranodal) and it accounts for 25 to 35% of all NHL. Primary lymphoma on the female genital tract (PLFGT) is a rare disease, comprising 0.2 to 1.1% of all extranodal lymphomas in the female population. In this paper, the authors report an extremely rare case of a 48-year-old woman who exhibited an abnormal uterine bleeding, pelvic pain, and dysmenorrhea history. The transvaginal ultrasound showed an anteverted uterus measuring 153 cm in volume, with intramural leiomyomas. She underwent a total laparoscopic hysterectomy with bilateral salpingectomy. The histologic evaluation of the specimen showed a follicular lymphoma with diffuse pattern in the endometrium. This report illustrates the difficulty in the diagnosis of primary lymphomas of the female genital tract.

摘要

原发性非霍奇金淋巴瘤(NHL)可起源于实体器官(结外)中的淋巴细胞,占所有NHL的25%至35%。女性生殖道原发性淋巴瘤(PLFGT)是一种罕见疾病,占女性人群所有结外淋巴瘤的0.2%至1.1%。在本文中,作者报告了一例极为罕见的病例,一名48岁女性,有异常子宫出血、盆腔疼痛和痛经病史。经阴道超声显示子宫前倾,体积为153立方厘米,伴有壁间平滑肌瘤。她接受了全腹腔镜子宫切除术及双侧输卵管切除术。标本的组织学评估显示子宫内膜有弥漫性滤泡性淋巴瘤。本报告说明了女性生殖道原发性淋巴瘤诊断的困难。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4cac/5828537/84ba0663833e/CRIOG2018-5065738.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4cac/5828537/84ba0663833e/CRIOG2018-5065738.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4cac/5828537/84ba0663833e/CRIOG2018-5065738.001.jpg

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本文引用的文献

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Gynecol Oncol. 2017 May;145(2):305-309. doi: 10.1016/j.ygyno.2017.02.043. Epub 2017 Mar 9.
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Primary B-cell lymphoma of the uterine cervix: Presentation in Pap-test slide and cervical biopsy.子宫颈原发性B细胞淋巴瘤:在巴氏涂片和宫颈活检中的表现
Diagn Cytopathol. 2017 Mar;45(3):235-238. doi: 10.1002/dc.23627. Epub 2016 Nov 8.
3
Laparoscopic Ovarian Transposition Before Pelvic Cancer Treatment: Ovarian Function and Fertility Preservation.
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Am J Surg Pathol. 2016 Sep;40(9):1217-23. doi: 10.1097/PAS.0000000000000683.
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