MOAP-1, UBR5 and cisplatin resistance in ovarian cancer.
作者信息
Eblen Scott T, Bradley Amber
机构信息
Department of Cell and Molecular Pharmacology and Experimental Therapeutics, Medical University of South Carolina, Charleston, SC 29425, USA.
出版信息
Transl Cancer Res. 2017 Feb;6(Suppl 1):S18-S21. doi: 10.21037/tcr.2017.02.01.
Abstract
摘要
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本文引用的文献
1
Downregulation of the proapoptotic protein MOAP-1 by the UBR5 ubiquitin ligase and its role in ovarian cancer resistance to cisplatin.泛素连接酶UBR5对促凋亡蛋白MOAP-1的下调作用及其在卵巢癌顺铂耐药中的作用
Oncogene. 2017 Mar 23;36(12):1698-1706. doi: 10.1038/onc.2016.336. Epub 2016 Oct 10.
2
Distinct functional domains of PNMA5 mediate protein-protein interaction, nuclear localization, and apoptosis signaling in human cancer cells.PNMA5的不同功能结构域介导人类癌细胞中的蛋白质-蛋白质相互作用、核定位及凋亡信号传导。
J Cancer Res Clin Oncol. 2016 Sep;142(9):1967-77. doi: 10.1007/s00432-016-2205-5. Epub 2016 Jul 16.
3
EDD enhances cell survival and cisplatin resistance and is a therapeutic target for epithelial ovarian cancer.EDD 增强细胞存活和顺铂耐药性，是上皮性卵巢癌的治疗靶点。
Carcinogenesis. 2014 May;35(5):1100-9. doi: 10.1093/carcin/bgt489. Epub 2013 Dec 30.
4
TRIP12 and UBR5 suppress spreading of chromatin ubiquitylation at damaged chromosomes.TRIP12 和 UBR5 抑制受损染色体上染色质泛素化的扩散。
Cell. 2012 Aug 17;150(4):697-709. doi: 10.1016/j.cell.2012.06.039. Epub 2012 Aug 9.
5
Modulator of Apoptosis 1: A Highly Regulated RASSF1A-Interacting BH3-Like Protein.凋亡调节因子1：一种受高度调控的与RASSF1A相互作用的类BH3蛋白。
Mol Biol Int. 2012;2012:536802. doi: 10.1155/2012/536802. Epub 2012 Jun 14.
6
The Trim39 ubiquitin ligase inhibits APC/CCdh1-mediated degradation of the Bax activator MOAP-1.Trim39 泛素连接酶抑制 APC/CCdh1 介导的 Bax 激活剂 MOAP-1 的降解。
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7
Molecular mechanisms of cisplatin resistance.顺铂耐药的分子机制。
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Protein kinase DYRK2 is a scaffold that facilitates assembly of an E3 ligase.蛋白激酶DYRK2是一种促进E3连接酶组装的支架蛋白。
Nat Cell Biol. 2009 Apr;11(4):409-19. doi: 10.1038/ncb1848. Epub 2009 Mar 15.
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TRIM39 is a MOAP-1-binding protein that stabilizes MOAP-1 through inhibition of its poly-ubiquitination process.TRIM39是一种与MOAP-1结合的蛋白质，它通过抑制MOAP-1的多聚泛素化过程来使其稳定。
Exp Cell Res. 2009 Apr 15;315(7):1313-25. doi: 10.1016/j.yexcr.2008.11.021. Epub 2008 Dec 9.
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Dynamics of RASSF1A/MOAP-1 association with death receptors.RASSF1A/MOAP-1与死亡受体的关联动态
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