血液透析患者的生活质量不仅受医学因素影响，还受心理社会因素影响：典范相关分析研究。
The Quality of Life of Hemodialysis Patients Is Affected Not Only by Medical but also Psychosocial Factors: a Canonical Correlation Study.
机构信息
Department of Psychiatry, School of Medicine, Kyungpook National University, Daegu, Korea.
Department of Internal Medicine, Catholic University of Daegu School of Medicine, Daegu, Korea.
出版信息
J Korean Med Sci. 2018 Apr 2;33(14):e111. doi: 10.3346/jkms.2018.33.e111.
BACKGROUND
The quality of life (QoL) of patients with end-stage renal disease (ESRD) is very poor, plausibly due to both psychosocial and medical factors. This study aimed to determine the relationship among psychosocial factors, medical factors, and QoL in patients with ESRD undergoing hemodialysis (HD).
METHODS
In total, 55 male and 47 female patients were evaluated (mean age, 57.1 ± 12.0 years). The QoL was evaluated using the Korean version of World Health Organization Quality of Life Scale-Abbreviated Version. The psychosocial factors were evaluated using the Hospital Anxiety and Depression Scale, Multidimensional Scale of Perceived Social Support, Montreal Cognitive Assessment, Pittsburgh Sleep Quality Index, and Zarit Burden Interview. The medical factors were assessed using laboratory examinations. Correlation and canonical correlation analyses were performed to investigate the association patterns.
RESULTS
The QoL was significantly correlated with the psychosocial factors, and to a lesser extent with the medical factors. The medical and psychosocial factors were also correlated. The canonical correlation analysis indicated a correlation between QoL and psychosocial factors (1st canonical correlation = 0.696, P < 0.001; 2nd canonical correlation = 0.421, P = 0.191), but not medical factors (1st canonical correlation = 0.478, P = 0.475; 2nd canonical correlation = 0.419, P = 0.751). The medical and psychosocial factors were also correlated (1st canonical correlation = 0.689, P < 0.001; 2nd canonical correlation = 0.603, P = 0.009).
CONCLUSION
Psychosocial factors influence QoL in patients with ESRD, and should thus be carefully considered when caring for these patients in clinical practice.
背景
终末期肾病（ESRD）患者的生活质量（QoL）非常差，这可能是由于心理社会和医疗因素共同作用的结果。本研究旨在确定接受血液透析（HD）的 ESRD 患者的心理社会因素、医疗因素与 QoL 之间的关系。
方法
共评估了 55 名男性和 47 名女性患者（平均年龄 57.1±12.0 岁）。使用世界卫生组织生活质量量表简表的韩语版评估 QoL。使用医院焦虑抑郁量表、多维感知社会支持量表、蒙特利尔认知评估量表、匹兹堡睡眠质量指数和 Zarit 负担访谈评估心理社会因素。使用实验室检查评估医疗因素。进行相关和典型相关分析以探究关联模式。
结果
QoL 与心理社会因素显著相关，与医疗因素的相关性较低。医疗因素和心理社会因素也相互关联。典型相关分析表明 QoL 与心理社会因素之间存在相关性（第 1 典型相关系数=0.696，P＜0.001；第 2 典型相关系数=0.421，P=0.191），而与医疗因素无相关性（第 1 典型相关系数=0.478，P=0.475；第 2 典型相关系数=0.419，P=0.751）。医疗因素和心理社会因素也相互关联（第 1 典型相关系数=0.689，P＜0.001；第 2 典型相关系数=0.603，P=0.009）。
结论
心理社会因素影响 ESRD 患者的 QoL，因此在临床实践中照顾这些患者时应予以重视。
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