Tanaka Satoshi
Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama University.
Yakugaku Zasshi. 2018;138(4):477-486. doi: 10.1248/yakushi.17-00181-4.
An increasing number of cases of research misconduct and whistle-blowing in the fields of medicine and life sciences has created public concern about research integrity. In Europe and the United States, there has been a large focus on poor reproducibility in life science research, and poor reproducibility is largely associated with research misconduct. Research integrity is equally crucial in the pharmaceutical sciences, which play an important role in medical and life sciences. Individual cases of research misconduct have not been investigated in detail in Japan, because it was generally believed that only researchers with strong or strange personalities would participate in misconduct. However, a better understanding of research misconduct will enable more in-depth discussions about research integrity, which is now known to be closely associated with normal research activities. Here I will introduce information on various contemporary activities being performed to create a sound research environment, drawn from practices in universities, pharmaceutical companies, and government agencies. I will also discuss ways in which individual researchers can promote research integrity.
医学和生命科学领域中研究不端行为及举报事件日益增多，引发了公众对研究诚信的关注。在欧洲和美国，生命科学研究的可重复性差备受关注，而可重复性差在很大程度上与研究不端行为相关。研究诚信在制药科学中同样至关重要，制药科学在医学和生命科学中发挥着重要作用。在日本，个别研究不端行为案例尚未得到详细调查，因为人们普遍认为只有性格强势或怪异的研究人员才会参与不端行为。然而，更好地理解研究不端行为将有助于就研究诚信进行更深入的讨论，现在已知研究诚信与正常研究活动密切相关。在此，我将介绍从大学、制药公司和政府机构的实践中汲取的关于营造良好研究环境的各种当代活动的信息。我还将讨论个别研究人员促进研究诚信的方法。
