Institute of Applied Health Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
Health Economics Unit, Institute of Applied Health Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
Syst Rev. 2018 Apr 2;7(1):54. doi: 10.1186/s13643-018-0718-5.
Childhood obesity is a major global public health problem, with governments increasingly having to undertake various strategies to reduce excess weight in their populations. Considering the increasing number of well-conducted intervention studies in the field of childhood obesity prevention, there are relatively few published economic evaluations. The proposed systematic review will explore the methods of these economic evaluations, examine the limitations and establish the evidence base for cost-effectiveness analyses.
METHODS/DESIGN: Systematic review methodology will be applied to identify, select and extract data from published economic evaluation studies (trial-based, non-trial based, simulation-based, decision model and trial based model economic evaluations) of obesity prevention and/or treatment interventions in children and adolescents. A systematic literature search will be conducted using bibliographic databases (MEDLINE, EMBASE, CINAHL, Web of Science, EconLit, PsycINFO, Cochrane Library, Centre for Reviews and Dissemination (CRD) and Cost-Effectiveness Analysis (CEA) Registry). The review will only include full economic evaluations. There will be no restrictions based on language, perspective, follow-up duration, sample size, country or setting. To minimise selection bias, translation of non-English language articles will be undertaken. The quality of included studies will be assessed. Following data extraction, a narrative synthesis of the results from the included studies will be undertaken. Subgroup analysis will be considered where deemed appropriate.
The findings from this review, which will include primary studies, will provide evidence to assist health policy decision makers interpret economic evaluations in this field. In addition, we will identify gaps in the current literature to inform future-related research.
Prospero CRD42017062236.
儿童肥胖是一个全球性的主要公共卫生问题，各国政府越来越多地不得不采取各种策略来减少其人口的超重问题。考虑到在儿童肥胖预防领域进行了越来越多精心设计的干预研究，发表的经济评估相对较少。拟议的系统评价将探讨这些经济评估的方法，检查其局限性，并为成本效益分析建立证据基础。
方法/设计：系统评价方法将用于识别、选择和提取已发表的儿童和青少年肥胖预防和/或治疗干预措施的经济评价研究（基于试验、非试验、基于模拟、决策模型和基于试验的经济评价）的数据。将使用书目数据库（MEDLINE、EMBASE、CINAHL、Web of Science、EconLit、PsycINFO、Cochrane 图书馆、评论和传播中心 (CRD) 和成本效益分析 (CEA) 登记处）进行系统文献检索。本评价仅包括完整的经济评价。不基于语言、视角、随访时间、样本量、国家或背景对其进行限制。为了尽量减少选择偏倚，将对非英语文章进行翻译。将对纳入研究的质量进行评估。在提取数据后，将对纳入研究的结果进行叙述性综合。在适当的情况下，将考虑进行亚组分析。
本评价将包括原始研究，其结果将为卫生政策决策者提供证据，以帮助他们解释该领域的经济评价。此外，我们将确定当前文献中的差距，为未来的相关研究提供信息。
PROSPERO CRD42017062236。
