Division of Pulmonary, Critical Care and Sleep Medicine, University Hospitals Cleveland Medical Center, Cleveland, Ohio.
Division of Pulmonary, Critical Care and Sleep Medicine, Louis Stokes Cleveland VA Medical Center, Cleveland, Ohio.
J Clin Sleep Med. 2018 Apr 15;14(4):541-548. doi: 10.5664/jcsm.7040.
To assess the interrater reliability and accuracy of overnight pulse oximetry (OPO) interpretations by pulmonary fellows using a comprehensive structured template and after a brief educational session.
Using the template, four pulmonary and critical care (PCC) fellows interpreted OPO saturation waveforms and parameters extracted from 50 adult consecutive in-laboratory sleep studies. The template included three saturation parameters (mean saturation, oxygen desaturation index [ODI], and cumulative desaturation time) and description of the saturation waveform. A scoring system was proposed combining waveform characteristics and ODI to determine the suspicion for moderate to severe sleep apnea. Waveform description and mean saturation determined the suspicion for cardiopulmonary disease (CPD). Cumulative desaturation time determined need for oxygen prescription. Apnea-hypopnea index was extracted from the sleep study results.
The overall interrater reliability for final recommendations (sleep apnea suspicion, presence of CPD, and oxygen prescription) was high (kappa = .81, 95% confidence interval [CI] .76-.88). Good agreement was noted in CPD evaluation and suspicion of moderate to severe sleep apnea (kappa = .70, 95% CI .46-.86 and kappa = .65, 95% CI .56-.77 respectively). The interrater reliability for oxygen prescription was in an excellent range (kappa = .98, 95% CI .91-1.00). The accuracy of a high sleep apnea suspicion score in detecting apnea-hypopnea index ≥ 15 events/h ranged from 88.0% to 94.0% (sensitivity 91.3% to 95.7%, specificity 81.5% to 92.6%). Desaturations due to CPD were identified by 75% of the raters as desaturations due to conditions other than sleep apnea.
A structured template for OPO interpretation can produce a high interrater agreement and good accuracy, and make it a reliable clinical tool.
A commentary on this article appears in this issue on page 497.
评估使用综合结构化模板和简短教育课程后,肺科住院医师对过夜脉搏血氧饱和度(OPO)解读的组内可靠性和准确性。
使用该模板,四位肺科和重症监护(PCC)住院医师对 50 例连续进行的实验室睡眠研究中的 OPO 饱和度波形和参数进行了解读。该模板包括三个饱和度参数(平均饱和度、氧减指数[ODI]和累计脱氧时间)和饱和度波形描述。提出了一种评分系统,结合波形特征和 ODI 来确定中度至重度睡眠呼吸暂停的可疑程度。波形描述和平均饱和度确定心肺疾病(CPD)的可疑程度。累计脱氧时间决定是否需要吸氧处方。睡眠研究结果中提取出呼吸暂停低通气指数。
最终建议(睡眠呼吸暂停可疑、CPD 存在和吸氧处方)的总体组内可靠性较高(kappa =.81,95%置信区间[CI].76-.88)。在 CPD 评估和中度至重度睡眠呼吸暂停的可疑程度方面,存在较好的一致性(kappa =.70,95%CI.46-.86 和 kappa =.65,95%CI.56-.77)。吸氧处方的组内可靠性处于极好范围(kappa =.98,95%CI.91-1.00)。高睡眠呼吸暂停可疑评分在检测呼吸暂停低通气指数≥15 次/小时方面的准确性范围为 88.0%至 94.0%(敏感性为 91.3%至 95.7%,特异性为 81.5%至 92.6%)。75%的评分者将 CPD 引起的脱氧识别为非睡眠呼吸暂停引起的脱氧。
用于 OPO 解读的结构化模板可以产生高度的组内一致性和良好的准确性,使其成为一种可靠的临床工具。
本文的评论见本期第 497 页。