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全科医生短暂性脑缺血发作培训对90天卒中结局的影响:一项整群随机对照试验的二次分析

Impact of General Practitioner Transient Ischemic Attack Training on 90-Day Stroke Outcomes: Secondary Analysis of a Cluster Randomized Controlled Trial.

作者信息

Ranta Annemarei, Dovey Susan, Gommans John, Tilyard Murray, Weatherall Mark

机构信息

Department of Medicine, University of Otago, Wellington, New Zealand; Department of Neurology, Capital & Coast District Health Board, New Zealand.

Department of General Practice and Rural Health, University of Otago, Dunedin, New Zealand.

出版信息

J Stroke Cerebrovasc Dis. 2018 Jul;27(7):2014-2018. doi: 10.1016/j.jstrokecerebrovasdis.2018.02.064. Epub 2018 Mar 30.

Abstract

GOALS

Many patients with transient ischemic attack (TIA) receive initial assessments by general practitioners (GPs) who may lack TIA management experience. In a randomized controlled trial (RCT), we showed that electronic decision support for GPs improves patient outcomes and guideline adherence. Some stroke services prefer to improve referrer expertise through TIA/stroke education sessions instead of promoting TIA decision aids or triaging tools. This is a secondary analysis of whether a GP education session influenced TIA management and outcomes.

MATERIALS AND METHODS

Post hoc analysis of a multicenter, single blind, parallel group, cluster RCT comparing TIA/stroke electronic decision support guided GP management with usual care to assess whether a pretrial TIA/stroke education session also affected RCT outcomes.

FINDINGS

Of 181 participating GPs, 79 (43.7%) attended an education session and 140 of 291 (48.1%) trial patients were managed by these GPs. There were fewer 90-day stroke events and 90-day vascular events or deaths in patients treated by GPs who attended education; 2 of 140 (1.4%) and 10 of 140 (7.1%) respectively, compared with those who did not; 5 of 151 (3.3%), and 14 of 151 (9.3%), respectively. Logistic regression for association between 90-day stroke and 90-day vascular events or death and education, however, was nonsignificant (odds ratio [OR] .42 (.08 to 2.22), P = .29 and .59 (95% confidence interval [CI] .27 to 1.29), P = .18 respectively. Guideline adherence was not improved by the education session: OR .84 (95% CI .49 to 1.45), P = .54.

CONCLUSION

In the described setting, a GP TIA/stroke education session did not significantly enhance guideline adherence or reduce 90-day stroke or vascular events following TIA.

摘要

目标

许多短暂性脑缺血发作(TIA)患者由可能缺乏TIA管理经验的全科医生(GP)进行初始评估。在一项随机对照试验(RCT)中,我们表明为全科医生提供电子决策支持可改善患者预后并提高指南依从性。一些卒中服务机构更倾向于通过TIA/卒中教育课程来提高转诊医生的专业知识,而不是推广TIA决策辅助工具或分诊工具。这是一项关于全科医生教育课程是否影响TIA管理及预后的二次分析。

材料与方法

对一项多中心、单盲、平行组、整群RCT进行事后分析,该试验比较了TIA/卒中电子决策支持指导下的全科医生管理与常规护理,以评估审前TIA/卒中教育课程是否也会影响RCT结果。

研究结果

181名参与的全科医生中,79名(43.7%)参加了教育课程,291名试验患者中的140名(48.1%)由这些全科医生管理。参加教育课程的全科医生治疗的患者90天卒中事件、90天血管事件或死亡较少;分别为140名中的2名(1.4%)和140名中的10名(7.1%),而未参加教育课程的全科医生治疗的患者分别为151名中的5名(3.3%)和151名中的14名(9.3%)。然而,90天卒中和90天血管事件或死亡与教育之间关联的逻辑回归无统计学意义(比值比[OR].42(.08至2.22),P = .29;以及.59(95%置信区间[CI].27至1.29),P = .18)。教育课程并未提高指南依从性:OR .84(95% CI .49至1.45),P = .54。

结论

在上述情况下,全科医生TIA/卒中教育课程并未显著提高指南依从性,也未减少TIA后90天的卒中或血管事件。

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