Liu Xiyang, Chen Zhenqi
1 Department of Stomatology, Tenth People's Hospital, Tongji University, Shanghai, China.
2 Department of Orthodontics, Ninth People's Hospital, Shanghai Jiao Tong University, Shanghai, China.
Cleft Palate Craniofac J. 2018 Nov;55(10):1367-1374. doi: 10.1177/1055665618768544. Epub 2018 Apr 3.
To identify the effects of palate repair on cranial base and maxillary morphology in patients with unilateral cleft lip and palate (UCLP) and to discover the relevance between cranial base and maxilla through cephalometric analysis.
Retrospective.
Thirty-seven UCLP patients with operated lip (OL) and unoperated palate constituted OL group and were classified into 5 cervical vertebral maturation (CVM) stages. Thirty-seven UCLP patients with operated lip and palate (OLP) and 37 noncleft people with skeletal class I malocclusion were CVM- and sex-matched with the OL group as OLP group and control group, respectively. CVM stage I and II were combined into group 1, CVM stage III to V were combined into group 2.
Lateral cephalograms of all participants were obtained.
Cephalometric analysis was employed, and data were compared among groups.
Length of posterior cranial base (Ba-S) of the OL group was shorter than controls in group 1; Ba-S and the ratio between length of posterior and anterior cranial base (Ba-S/S-N) of the OL and OLP groups were smaller than controls in group 2. No significant differences in cranial base were found between the OL and OLP groups. In group 1, patients of the OLP group showed smaller SNA, ANS-Ptm, and ANS-Ptm/S-N, and patients of the OL group showed smaller ANS-Ptm. In group 2, both OL and OLP groups had smaller sella-nasion-A point angle (SNA), projection distance between ANS and Ptm points on FH plane (ANS-Ptm), and the ratio between ANS-Ptm and anterior cranial base length (ANS-Ptm/S-N).
Palate repair seems to have no obvious effects on cranial base morphology in patients with UCLP. Those patients with lip operated, whether cleft palate operated or not, tend to have a smaller length of maxilla sagittally and this deformity progresses with age.
确定腭裂修复对单侧唇腭裂（UCLP）患者颅底和上颌骨形态的影响，并通过头影测量分析发现颅底与上颌骨之间的相关性。
回顾性研究。
37名单侧唇腭裂且唇已修复（OL）但腭裂未修复的患者组成OL组，并分为5个颈椎成熟度（CVM）阶段。37名单侧唇腭裂且唇和腭裂均已修复（OLP）的患者以及37名骨骼I类错牙合的非腭裂患者分别与OL组进行CVM阶段和性别匹配，作为OLP组和对照组。CVM I期和II期合并为第1组，CVM III期至V期合并为第2组。
获取所有参与者的头颅侧位片。
采用头影测量分析，并对组间数据进行比较。
在第1组中，OL组的后颅底长度（Ba-S）短于对照组；在第2组中，OL组和OLP组的Ba-S以及后颅底与前颅底长度之比（Ba-S/S-N）均小于对照组。OL组和OLP组之间在颅底方面未发现显著差异。在第1组中，OLP组患者的SNA、ANS-Ptm以及ANS-Ptm/S-N较小，OL组患者的ANS-Ptm较小。在第2组中，OL组和OLP组的蝶鞍点-鼻根点-A点角（SNA）、FH平面上ANS点与Ptm点之间的投影距离（ANS-Ptm）以及ANS-Ptm与前颅底长度之比（ANS-Ptm/S-N）均较小。
腭裂修复似乎对单侧唇腭裂患者的颅底形态无明显影响。那些唇已修复的患者，无论腭裂是否修复，矢状向上颌骨长度往往较小，且这种畸形会随着年龄增长而进展。
