通过磁共振标记成像应变分析与氟脱氧葡萄糖正电子发射断层扫描积聚及磁共振延迟钆增强对比，对心脏结节病中的局灶性心肌损伤进行特征分析。
Focal Myocardial Damage in Cardiac Sarcoidosis Characterized by Strain Analysis on Magnetic Resonance Tagged Imaging in Comparison with Fluorodeoxyglucose Positron Emission Tomography Accumulation and Magnetic Resonance Late Gadolinium Enhancement.
作者信息
Watanabe Yoshiaki, Nishii Tatsuya, Shimoyama Shinsuke, Ito Tatsuro, Mori Shumpei, Kono Atsushi K, Takahashi Satoru, Hirata Ken-Ichi, Sugimura Kazuro
机构信息
From the Department of Radiology, and.
Division of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Japan.
出版信息
J Comput Assist Tomogr. 2018 Jul/Aug;42(4):607-613. doi: 10.1097/RCT.0000000000000733.
OBJECTIVE
The aims of this study were to characterize focal myocardial damage of cardiac sarcoidosis by strain analysis and to compare it with late gadolinium enhancement (LGE) and fluorodeoxyglucose (FDG) positron emission tomography.
METHODS
We reviewed 208 segments from 13 cardiac sarcoidosis patients and measured the circumferential strain (Ecc) and the strain change per second (Ecc rate). The mean Ecc and Ecc rate values were compared between the FDG(+) and FDG(-), and the LGE(+) and LGE(-) segments using Welch's t test.
RESULTS
The peak and max Ecc rates were better in the LGE(-) segments than in the LGE(+) segments (-11.8 vs -8.9%, 40.5 vs 29.7%/s, both P < 0.001). The max Ecc rate was higher in the FDG(-) segments than in the FDG(+) segments (39.2 vs 31.7%/s, P < 0.001), but the peak Ecc did not differ between the FDG(+) and FDG(-) segments (-11.2 vs -10.1%, P = 0.17).
CONCLUSIONS
Strain analysis could reveal focal myocardial damage in the FDG(+) or the LGE(+) segments.
目的
本研究旨在通过应变分析对心脏结节病的局灶性心肌损伤进行特征描述，并将其与钆延迟增强（LGE）及氟脱氧葡萄糖（FDG）正电子发射断层扫描进行比较。
方法
我们回顾了13例心脏结节病患者的208个节段，并测量了圆周应变（Ecc）及每秒应变变化率（Ecc率）。使用韦尔奇t检验比较FDG（+）和FDG（-）节段以及LGE（+）和LGE（-）节段之间的平均Ecc和Ecc率值。
结果
LGE（-）节段的峰值和最大Ecc率优于LGE（+）节段（分别为-11.8%对-8.9%，40.5%/秒对29.7%/秒，P均<0.001）。FDG（-）节段的最大Ecc率高于FDG（+）节段（39.2%/秒对31.7%/秒，P<0.001），但FDG（+）和FDG（-）节段之间的峰值Ecc无差异（-11.2%对-10.1%，P=0.17）。
结论
应变分析可揭示FDG（+）或LGE（+）节段中的局灶性心肌损伤。
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