Niu C Q, Jiang H, Zhou S Y, Shen G, Li H B, Zhang J
Department of Interventional and Vascular Anomalies, Guangzhou Women Children Medical Center, Guangzhou 510623, China.
Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2018 Mar 7;53(3):209-213. doi: 10.3760/cma.j.issn.1673-0860.2018.03.008.
To evaluate the safety and efficacy of foam sclerotherapy with polidocanol for the treatment of venous malformation in the oropharynx. The clinical data of 21 children with venous malformation in the oropharynx treated by foam sclerotherapy were retrospectively analyzed. There were 10 males and 11 females, ranging in age from 1 month to 13 years, with a median age of 2.3 years. MRI was performed in all children, and the diagnosis was further confirmed by radiography. After general anesthesia, the oropharynx was exposed by opening device. Scalp acupuncture was used to pucture lesions and polidocanol foam was injected after the nidus was confirmed by digital subtraction angiography(DSA). The follow-up time ranged from 2-29 months, with a mean time of 15 months. The clinical symptoms, imaging data, therapeutic effects and postoperative complications were evaluated. Total numbers of treatment were 52 times, 1-6 times/case; 13 cases were cured, 7 cases was relieved and no response in one case. Postoperative swelling in 13 cases, fever in 3 cases, local mucosal ulcer in 2 cases, difficult extubation in 2 cases. No nerve injury, swallowing function damage and cardiopulmonary accidents were found in all patients. Foam sclerotherapy with polidocanol in the treatment of venous malformation in the oropharynx is a safe and effective method.
评估聚多卡醇泡沫硬化疗法治疗口咽部静脉畸形的安全性和有效性。回顾性分析21例采用泡沫硬化疗法治疗口咽部静脉畸形患儿的临床资料。其中男10例，女11例，年龄1个月至13岁，中位年龄2.3岁。所有患儿均行MRI检查，并经影像学检查进一步确诊。全身麻醉后，用开口器暴露口咽部。采用头皮针穿刺病变，数字减影血管造影（DSA）确定病灶后注入聚多卡醇泡沫。随访时间2～29个月，平均15个月。评估临床症状、影像学资料、治疗效果及术后并发症。治疗总次数为52次，每例1～6次；治愈13例，缓解7例，1例无效。术后13例出现肿胀，3例发热，2例局部黏膜溃疡，2例拔管困难。所有患者均未发现神经损伤、吞咽功能损害及心肺意外。聚多卡醇泡沫硬化疗法治疗口咽部静脉畸形是一种安全有效的方法。
