Modeling Alzheimer's and Other Age Related Human Diseases in Embryonic Systems.

Modeling human disease in animals is an important strategy to discover potential methods of intervention. We suggest that there is much to be gained by employing a multi-model approach that takes advantage of different animal systems used in the laboratory simultaneously. We use the example of modeling Alzheimer's disease in , , and to illustrate how such an approach can be employed to investigate the pathophysiology of the disease.