Olson Jody C
University of Kansas Medical Center, 3901 Rainbow Blvd., MS 1023, Kansas City, Kansas, 66160, USA.
Curr Treat Options Gastroenterol. 2018 Jun;16(2):241-252. doi: 10.1007/s11938-018-0182-2.
Cirrhosis is a major worldwide health problem which results in a high level of morbidity and mortality. Patients with cirrhosis who require intensive care support have high mortality rates of near 50%. The goal of this review is to address the management of common complications of cirrhosis in the ICU.
Recent epidemiological studies have shown an increase in hospitalizations due to advanced liver disease with an associated increase in intensive care utilization. Given an increasing burden on the healthcare system, it is imperative that we strive to improve our management cirrhotic patients in the intensive care unit. Large studies evaluating the management of patients in the intensive care setting are lacking. To date, most recommendations are based on extrapolation of data from studies in cirrhosis outside of the ICU or by applying general critical care principles which may or may not be appropriate for the critically ill cirrhotic patient. Future research is required to answer important management questions.
肝硬化是一个全球性的主要健康问题,导致高发病率和死亡率。需要重症监护支持的肝硬化患者死亡率接近50%,居高不下。本综述的目的是探讨重症监护病房(ICU)中肝硬化常见并发症的管理。
最近的流行病学研究表明,晚期肝病导致的住院人数增加,同时重症监护的使用率也相应增加。鉴于医疗系统负担日益加重,我们必须努力改善对重症监护病房中肝硬化患者的管理。目前缺乏评估重症监护环境下患者管理的大型研究。迄今为止,大多数建议是基于对ICU以外的肝硬化研究数据的推断,或者是应用可能适用于也可能不适用于重症肝硬化患者的一般重症监护原则。需要未来的研究来回答重要的管理问题。