儿童全身瘦体重估计预测方程的开发与交叉验证
Development and cross-validation of predictive equation for estimating total body lean in children.
作者信息
Colica Carmela, Di Renzo Laura, Gualtieri Paola, Romano Lorenzo, Costa de Miranda Renata, De Lorenzo Antonino, Purificato Ivana
机构信息
CNR, IBFM UOS, Università degli Studi "Magna Graecia" di Catanzaro, Campus "Salvatore Venuta", Germaneto, Catanzaro, Italy.
Sezione di Nutrizione Clinica e Nutrigenomica, Dipartimento di Biomedicina e Prevenzione, Università degli Studi di Roma "Tor Vergata", Rome, Italy.
出版信息
Ann Ist Super Sanita. 2018 Jan-Mar;54(1):20-27. doi: 10.4415/ANN_18_01_06.
AIM
To develop and cross-validate a predictive equation for estimating lean body mass (LBM) in children, based on bioelectrical impedance analysis (BIA) and anthropometric parameters, and to compare our equation with other predictive methods.
METHODS
We evaluated body composition of 155 children (age 5-14 years) by BIA and dual energy X-ray absorptiometry (DXA). Children were divided in two groups: developing set and cross-validation set. Statistical analysis as multiple regression and Bland-Altman methods were performed.
RESULTS
From developing set (105 children) a predictive LBM (kg) equation was created. From the cross-validated set (35 children), our equation was seen to agree with LBM (kg) by DXA. On the contrary, LBM predicted by Schaefer's equation and BIA did not agree with the criterion measure.
CONCLUSIONS
This cross-validated equation can be useful in epidemiological studies and also in clinical practice, permitting a better definition and follow up of children's body composition.
目的
基于生物电阻抗分析（BIA）和人体测量参数，开发并交叉验证一个用于估算儿童瘦体重（LBM）的预测方程，并将我们的方程与其他预测方法进行比较。
方法
我们通过BIA和双能X线吸收法（DXA）评估了155名儿童（年龄5 - 14岁）的身体成分。儿童被分为两组：开发集和交叉验证集。进行了多元回归和Bland - Altman方法的统计分析。
结果
从开发集（105名儿童）创建了一个预测LBM（千克）的方程。在交叉验证集（35名儿童）中，我们的方程与通过DXA得出的LBM（千克）相符。相反，Schaefer方程和BIA预测的LBM与标准测量结果不一致。
结论
这个经过交叉验证的方程在流行病学研究以及临床实践中可能有用，有助于更好地定义和跟踪儿童的身体成分。
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