Divisão de Urologia, Faculdade de Medicina da Universidade de São Paulo - FMUSP, SP, Brasil.
Int Braz J Urol. 2018 Jul-Aug;44(4):765-770. doi: 10.1590/S1677-5538.IBJU.2017.0605.
The urinary bladder diverticula (BD) secondary to benign prostatic hyperplasia (BPH) is a complication that can lead to urinary stasis, stone, urinary tract infection (UTI) and tumors. It's role in acute urinary retention (AUR) is not totally understood.
To determine the effect of BD size on AUR rates in patients with BPH candidates to surgery.
We performed a retrospective cohort study of 47 patients with BPH and BD who underwent BPH surgery associated to complete bladder diverticulectomy from 2006 to 2016. We analyzed risk factors for AUR in patients with BD using univariate, multivariate and correlation analysis.
There was a difference in the size of the diverticula, with 6.8 cm vs. 4.5 cm among patients with and without AUR respectively (p=0.005). The ROC curve showed a correlation between the size of BD and the risk of AUR. The value of 5.15 cm presented a sensitivity of 73% and a specificity of 72%. The area under the curve was 0.75 (p=0.01). Comparing groups with BD >5.0 cm vs. ≤5.0 cm, the AUR incidence was 74% and 27.8% respectively with an OR of 2.65 (1.20-5.85) (p=0.005). In the multivariate analysis, only the size of the diverticula reached statistical significance (p=0.012).
The diameter of BD is an independent risk factor for AUR in patients with BPH and BD who are candidates to surgery. A diameter greater than 5.15 cm increases the risk of AUR.
良性前列腺增生(BPH)继发的膀胱憩室(BD)是一种可导致尿潴留、结石、尿路感染(UTI)和肿瘤的并发症。它在急性尿潴留(AUR)中的作用尚未完全阐明。
确定 BPH 患者 BD 大小对手术候选者 AUR 发生率的影响。
我们对 2006 年至 2016 年间接受 BPH 手术联合完整膀胱憩室切除术的 47 例 BPH 合并 BD 患者进行了回顾性队列研究。我们使用单变量、多变量和相关分析来分析 BD 患者发生 AUR 的危险因素。
BD 大小存在差异,AUR 患者的憩室大小为 6.8cm,而无 AUR 患者的憩室大小为 4.5cm(p=0.005)。ROC 曲线显示 BD 大小与 AUR 风险之间存在相关性。BD 大小为 5.15cm 时,敏感性为 73%,特异性为 72%。曲线下面积为 0.75(p=0.01)。比较 BD>5.0cm 组与≤5.0cm 组,AUR 发生率分别为 74%和 27.8%,OR 为 2.65(1.20-5.85)(p=0.005)。在多变量分析中,只有憩室大小达到统计学意义(p=0.012)。
BD 直径是 BPH 合并 BD 且拟行手术患者发生 AUR 的独立危险因素。直径大于 5.15cm 会增加 AUR 的风险。