Neuropsychology and Applied Cognitive Neuroscience Laboratory, CAS Key Laboratory of Mental Health, Institute of Psychology, and Department of Psychology, University of Chinese Academy of Sciences.
Department of Psychosis Studies, Institute of Psychiatry, Psychology, and Neuroscience, King's College London.
Neuropsychology. 2018 Mar;32(3):329-336. doi: 10.1037/neu0000393.
The present study aimed to investigate the neural basis of information matching during sensory integration using a spatial-temporal matching task in healthy individuals.
A total of 37 healthy participants were recruited to match spatial dots with an auditory tone sequence in a 3T GE Discovery MR750 scanner. In addition, they were examined with the sensory integration subscale of the Cambridge Neurological Inventory.
We found that the bilateral occipital-parietal conjunction cortex and the precentral frontal gyrus were activated during the matching condition rather than in the nonmatching condition. Activation of the occipital-parietal conjunction cortex was associated with integration of information across visual and auditory modalities, whereas activation of the precentral frontal gyrus was associated with decision making of movements. In addition, activation of the left superior frontal gyrus was associated with scores on the sensory integration subscale of the Cambridge Neurological Inventory.
These findings suggest that the bilateral occipital-parietal conjunction cortex is responsible for matching information input from multiple modalities during audiovisual sensory integration. (PsycINFO Database Record
本研究旨在使用健康个体的时空匹配任务，探究感觉整合过程中的信息匹配的神经基础。
共招募 37 名健康参与者，在 3T GE Discovery MR750 扫描仪上匹配空间点与听觉音调序列。此外，他们还接受了剑桥神经学量表的感觉整合子量表的检查。
我们发现，双侧枕顶联合皮层和中央前回在匹配条件下激活，而在不匹配条件下不激活。枕顶联合皮层的激活与跨视觉和听觉模式的信息整合有关，而中央前回的激活与运动决策有关。此外，左额上回的激活与剑桥神经学量表感觉整合子量表的得分相关。
这些发现表明，双侧枕顶联合皮层负责在视听感觉整合过程中匹配来自多个模态的信息输入。
