Ioannidis Ioannis, Huang Jui-Han
Hospital of the University of Pennsylvania (I.I.) Pennsylvania Hospital, University of Pennsylvania Health System (J.H.H.), Philadelphia, Pennsylvania.
Int J Gynecol Pathol. 2019 May;38(3):253-257. doi: 10.1097/PGP.0000000000000505.
Extra-ovarian neoplasms incidentally discovered during cesarean section are very rare. Here we report a case of inflammatory myofibroblastic tumor found during cesarean section of a 30-year-old, full-term woman, forming a mass in her cul-de-sac. Histology revealed an extensively decidualized spindle cell process, positive for anaplastic large cell lymphoma kinase (ALK) through immunohistochemistry and fluorescent in situ hybridization (FISH). To the best of our knowledge, this is the first presentation of inflammatory myofibroblastic tumor in this location without concurrent intrauterine component, that additionally demonstrates this degree of decidualization, mimicking ectopic decidua.
剖宫产术中偶然发现的卵巢外肿瘤非常罕见。在此,我们报告一例在一名30岁足月孕妇剖宫产术中发现的炎性肌纤维母细胞瘤,该肿瘤在其道格拉斯窝形成肿块。组织学检查显示广泛蜕膜化的梭形细胞过程,通过免疫组织化学和荧光原位杂交(FISH)检测,间变性大细胞淋巴瘤激酶(ALK)呈阳性。据我们所知,这是该部位首次出现无并发宫内成分的炎性肌纤维母细胞瘤,且额外表现出这种程度的蜕膜化,酷似异位蜕膜。