Ji Hongyan, Chen Li, Sun Xiaojun, Li Xiuli, Chen Wei, Zhao Ping, Wang Yulin
Department of Pediatrics, Shandong Provincial Hospital Affiliated to Shandong University, Shandong University, Jinan, Shandong.
Department of Pediatrics, Anhui Provincial Cancer Hospital, Anhui, China.
J Pediatr Hematol Oncol. 2018 Aug;40(6):e355-e358. doi: 10.1097/MPH.0000000000001141.
Hepatitis-associated aplastic anemia (HAAA) is a variant of acquired aplastic anemia in which bone marrow failure follows the development of an acute episode of seronegative hepatitis. HAAA occurs most frequently in male children and is lethal if left untreated. Antilymphocyte globulin, antithymocyte globulin, and allogeneic bone marrow transplantation have been used in the treatment of this disease. In this work, we report the case of a 3-year-old boy with HAAA treated successfully with immunosuppressive therapy.
肝炎相关性再生障碍性贫血（HAAA）是获得性再生障碍性贫血的一种变体，其骨髓衰竭发生在血清阴性肝炎急性发作之后。HAAA最常发生于男童，若不治疗则会致命。抗淋巴细胞球蛋白、抗胸腺细胞球蛋白及同种异体骨髓移植已用于治疗该疾病。在本研究中，我们报告了一名3岁患HAAA的男童成功接受免疫抑制治疗的病例。
