Levy G
Laboratoire du département d'Anesthésie-Réanimation, CHU Timone, Marseille.
Presse Med. 1987 Oct 24;16(35):1750-4.
The biochemical diagnosis of myocardial infarction is mainly based on assays of serum enzymes. The most commonly used markers are creatine kinase, lactic dehydrogenase and aspartate amino-transferase. They are useful to diagnose the infarction, determine its time of onset and evaluate its importance. Changes in concentration of these enzymes are measured during their release from cells, their diffusion and their elimination in order to establish their characteristic profile in the acute phase of the disease. The diagnostic value and contribution to the prognosis of these tests are detailed. Heart diseases other than myocardial infarction, and other diseases in which serum levels are raised are described. The other laboratory abnormalities associated with myocardial infarction are listed.
心肌梗死的生化诊断主要基于血清酶检测。最常用的标志物是肌酸激酶、乳酸脱氢酶和天冬氨酸转氨酶。它们有助于诊断梗死、确定其发病时间并评估其严重程度。在这些酶从细胞释放、扩散及清除过程中检测其浓度变化,以确定它们在疾病急性期的特征性变化情况。详细阐述了这些检测的诊断价值及其对预后的作用。还描述了除心肌梗死之外的其他心脏病以及血清水平升高的其他疾病。列出了与心肌梗死相关的其他实验室异常情况。