Choi W, Shin J H, Kim P H, Han K, Ohm J Y, Kim J H, Kim J W
Department of Radiology, Severance Hospital, Research Institute of Radiological Science, Yonsei University, College of Medicine, 50-1, Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea.
Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul, 138-736, Republic of Korea.
Clin Radiol. 2018 Jul;73(7):665-671. doi: 10.1016/j.crad.2018.02.019. Epub 2018 Apr 2.
To evaluate the safety and efficacy of repeated pelvic arterial embolisation (PAE) for uncontrolled postpartum haemorrhage (PPH) after a single session of PAE and to compare angiographic findings between the two sessions of PAE.
A total of 23 consecutive patients (age range, 23-44 years) who underwent repeated PAE for uncontrolled PPH between March 2001 and January 2016 in Severance Hospital were reviewed. The interval times between the two sessions of PAE, the angiographic findings, embolic materials, arteries embolised during PAE, and the clinical outcomes were reviewed retrospectively.
Overall clinical success was achieved after repeated PAE in 21 of 23 patients (91.3%). There were no procedure-related, major complications. On angiography, active bleeding from the uterine collateral arteries was more frequently observed in the second session of PAE (p>0.05), and embolisation of the anterior division of the internal iliac artery was significantly higher during the second session of PAE. Use of permanent embolic materials was significantly higher during the second session of PAE. Recanalisation of a previously embolised artery was identified in 14 patients (60.9%) during the second session.
Repeated PAE is safe and effective for managing recurrent bleeding after a single session of PAE. Repeated PAE is related to a higher chance of embolisation of the anterior division of the internal iliac artery, with the use of permanent embolic materials. Recanalisation of a previously embolised artery seems to be a principal source of rebleeding during a repeated session of PAE.
评估单次盆腔动脉栓塞术(PAE)后对控制产后出血(PPH)无效时重复进行PAE的安全性和有效性,并比较两次PAE的血管造影结果。
回顾性分析2001年3月至2016年1月在Severance医院因PPH控制无效而接受重复PAE的23例连续患者(年龄范围23 - 44岁)。回顾两次PAE之间的间隔时间、血管造影结果、栓塞材料、PAE期间栓塞的动脉以及临床结局。
23例患者中有21例(91.3%)在重复PAE后取得了总体临床成功。没有与手术相关的严重并发症。在血管造影中,第二次PAE时更频繁地观察到子宫侧支动脉的活动性出血(p>0.05),并且第二次PAE期间髂内动脉前支的栓塞率显著更高。第二次PAE期间永久性栓塞材料的使用显著更多。在第二次PAE期间,14例患者(60.9%)发现先前栓塞的动脉再通。
重复PAE对于单次PAE后复发性出血的处理是安全有效的。重复PAE与髂内动脉前支栓塞的可能性更高以及永久性栓塞材料的使用有关。先前栓塞动脉的再通似乎是重复PAE期间再出血的主要来源。