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关于初产妇、经产妇及阿氏评分对新生儿脐血全血细胞计数和铁代谢指标的研究

Study of Complete Haemogram and Iron Profile From Cord Blood of Newborn with Respect to Primigravida, Multigravida and Apgar Score.

作者信息

Mondal Madhumita, Sinha Swapan Kumar, Sengupta Moumita, Bose Debdas, Saha Sudip, Chaudhuri Utpal

机构信息

1Department of Pathology, IPGMER, Kolkata, 700020 India.

2Department of Pathology, Medical College Hospital, Kolkata, 700073 India.

出版信息

Indian J Hematol Blood Transfus. 2018 Apr;34(2):310-313. doi: 10.1007/s12288-017-0860-6. Epub 2017 Aug 23.

Abstract

Study of different parameters of cord blood usually reflects neonatal health status. One of the widely used system for assessing neonatal health is APGAR score. It is assed at 1 and 5 min from baby's birth. Immediate medical care may improve 5 min score of neonate who showed poor score at 1 min. The main objective of this study is to establish whether any correlation exists between complete hemogram and iron profile with APGAR score and gravid of mother. Cord blood was collected from 96 new born, delivered vaginally, mothers having no chronic medical disease. Different parameters of complete hemogram were assessed along with iron profile and statistical analysis was done by Graph pad Instat3 soft ware. Statistically significant correlation exists between APGAR score (5 min) and MCV ( = 0.005), MCHC ( = 0.016), nRBC ( = 0.002), platelet count ( = 0.001), RDW ( = 0.001). Statistically weak correlation exists between TLC ( = 0.08). Comparing complete blood count with gravid of mother by unpaired test significant correlation was obtained for HCT ( = 0.035) and RDW ( = 0.03). Apgar score and complete hemogram from cord blood are both non-invasive procedure which help us to asses fetal wellbeing as well as requirement of immediate management. Further more studies are essential to establish the relationship.

摘要

对脐带血不同参数的研究通常反映新生儿的健康状况。评估新生儿健康状况广泛使用的系统之一是阿氏评分。在婴儿出生后1分钟和5分钟时进行评估。对于出生后1分钟时评分较低的新生儿,及时的医疗护理可能会提高其5分钟时的评分。本研究的主要目的是确定全血细胞计数和铁代谢指标与阿氏评分及母亲妊娠情况之间是否存在任何相关性。从96例经阴道分娩、母亲无慢性疾病的新生儿中采集脐带血。评估全血细胞计数的不同参数以及铁代谢指标,并使用Graph pad Instat3软件进行统计分析。阿氏评分(5分钟时)与平均红细胞体积(P = 0.005)、平均血红蛋白浓度(P = 0.016)、有核红细胞(P = 0.002)、血小板计数(P = 0.001)、红细胞分布宽度(P = 0.001)之间存在统计学显著相关性。淋巴细胞计数(P = 0.08)之间存在统计学弱相关性。通过非配对t检验比较母亲妊娠情况与全血细胞计数,发现血细胞比容(P = 0.035)和红细胞分布宽度(P = 0.03)存在显著相关性。脐带血的阿氏评分和全血细胞计数都是非侵入性检查,有助于我们评估胎儿健康状况以及是否需要立即进行处理。进一步的研究对于确立这种关系至关重要。

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