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Refractory ALK-Positive Anaplastic Large Cell Lymphoma: Long Term Survival with Crizotinib.难治性ALK阳性间变性大细胞淋巴瘤：克唑替尼治疗的长期生存
Indian J Hematol Blood Transfus. 2018 Apr;34(2):353-354. doi: 10.1007/s12288-017-0889-6. Epub 2017 Nov 4.
2
A Phase I/II Study of Crizotinib for Recurrent or Refractory Anaplastic Lymphoma Kinase-Positive Anaplastic Large Cell Lymphoma and a Phase I Study of Crizotinib for Recurrent or Refractory Neuroblastoma : Study Protocol for a Multicenter Single-arm Open-label Trial.克唑替尼用于复发或难治性间变性淋巴瘤激酶阳性间变性大细胞淋巴瘤的I/II期研究及克唑替尼用于复发或难治性神经母细胞瘤的I期研究：一项多中心单臂开放标签试验的研究方案
Acta Med Okayama. 2018 Aug;72(4):431-436. doi: 10.18926/AMO/56184.
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Three Years Sustained Complete Remission Achieved in a Primary Refractory ALK-Positive Anaplastic T Large Cell Lymphoma Treated with Crizotinib.克唑替尼治疗原发性难治性ALK阳性间变性大细胞淋巴瘤实现三年持续完全缓解
Rare Tumors. 2016 Jun 28;8(2):6266. doi: 10.4081/rt.2016.6266.
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ALK expression plays different roles in anaplastic large-cell lymphomas and outcome of crizotinib use in relapsed/refractory ALK+ patients in a Chinese population.间变性淋巴瘤激酶（ALK）表达在间变性大细胞淋巴瘤中发挥不同作用，以及在中国人群复发/难治性ALK阳性患者中使用克唑替尼的疗效。
Ann Hematol. 2018 Jan;97(1):149-159. doi: 10.1007/s00277-017-3166-8. Epub 2017 Nov 17.
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Blockade of crizotinib-induced BCL2 elevation in ALK-positive anaplastic large cell lymphoma triggers autophagy associated with cell death.阻断克唑替尼诱导的 ALK 阳性间变大细胞淋巴瘤中 BCL2 的上调可触发与细胞死亡相关的自噬。
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Crizotinib as salvage and maintenance with allogeneic stem cell transplantation for refractory anaplastic large cell lymphoma.克唑替尼作为异体干细胞移植治疗难治性间变大细胞淋巴瘤的挽救和维持治疗。
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Anaplastic lymphoma kinase-positive anaplastic large cell lymphoma: current and future perspectives in adult and paediatric disease.间变性淋巴瘤激酶阳性间变性大细胞淋巴瘤：成人和儿童疾病的现状与未来展望
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Targeting autophagy enhances the anti-tumoral action of crizotinib in ALK-positive anaplastic large cell lymphoma.靶向自噬可增强克唑替尼对ALK阳性间变性大细胞淋巴瘤的抗肿瘤作用。
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Treatment Optimization for Brain Metastasis from Anaplastic Lymphoma Kinase Rearrangement Non-Small-Cell Lung Cancer.治疗间变性淋巴瘤激酶重排非小细胞肺癌脑转移
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Crizotinib in anaplastic lymphoma kinase-positive anaplastic large cell lymphoma in the setting of renal insufficiency: a case report.克唑替尼用于肾功能不全情况下间变性淋巴瘤激酶阳性间变性大细胞淋巴瘤：一例报告
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Crizotinib in Combination With Chemotherapy for Pediatric Patients With ALK+ Anaplastic Large-Cell Lymphoma: The Results of Children's Oncology Group Trial ANHL12P1.克唑替尼联合化疗治疗儿童 ALK+间变大细胞淋巴瘤：儿童肿瘤学组 ANHL12P1 试验结果。
J Clin Oncol. 2023 Apr 10;41(11):2043-2053. doi: 10.1200/JCO.22.00272. Epub 2022 Dec 19.

本文引用的文献

1
The pathobiology of the oncogenic tyrosine kinase NPM-ALK: a brief update.致癌酪氨酸激酶 NPM-ALK 的病理生物学：简要更新。
Ther Adv Hematol. 2013 Apr;4(2):119-31. doi: 10.1177/2040620712471553.
2
Safety and activity of crizotinib for paediatric patients with refractory solid tumours or anaplastic large-cell lymphoma: a Children's Oncology Group phase 1 consortium study.克唑替尼治疗儿童难治性实体瘤或间变大细胞淋巴瘤的安全性和活性：儿童肿瘤学组 1 期联盟研究。
Lancet Oncol. 2013 May;14(6):472-80. doi: 10.1016/S1470-2045(13)70095-0. Epub 2013 Apr 16.
3
Anaplastic large cell lymphoma, ALK-positive.间变大细胞淋巴瘤，ALK 阳性。
Crit Rev Oncol Hematol. 2012 Aug;83(2):293-302. doi: 10.1016/j.critrevonc.2012.02.005. Epub 2012 Mar 21.
4
Crizotinib in anaplastic large-cell lymphoma.克唑替尼治疗间变性大细胞淋巴瘤
N Engl J Med. 2011 Feb 24;364(8):775-6. doi: 10.1056/NEJMc1013224.

Refractory ALK-Positive Anaplastic Large Cell Lymphoma: Long Term Survival with Crizotinib.

作者信息

Ganesan Prasanth, Joshua Thanda, Sundersingh Shirley, Sagar Tenali Gnana

机构信息

1Department of Medical Oncology, Cancer Institute (WIA), Sardar Patel Road, Adyar, Chennai, Tamil Nadu 600020 India.

2Department of Pathology, Cancer Institute (WIA), Adyar, Chennai, 600020 India.

出版信息

Indian J Hematol Blood Transfus. 2018 Apr;34(2):353-354. doi: 10.1007/s12288-017-0889-6. Epub 2017 Nov 4.

DOI:10.1007/s12288-017-0889-6
PMID:29622884
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5884998/
Abstract
摘要