易于功能化的 AAA-DDD 三重氢键基序。

Readily functionalized AAA-DDD triply hydrogen-bonded motifs.

机构信息

Key Laboratory of Optoelectronic Chemical Materials and Devices of Ministry of Education, School of Chemical and Environmental Engineering, Jianghan University, Wuhan, Hubei 430056, China.

出版信息

Org Biomol Chem. 2018 Apr 25;16(16):2947-2954. doi: 10.1039/c8ob00479j.

DOI:10.1039/c8ob00479j

PMID:29623318

Abstract

Herein we present a new, readily functionalized AAA-DDD hydrogen bond array. A novel AAA monomeric unit (3a-b) was obtained from a two-step synthetic procedure starting with 2-aminonicotinaldehyde via microwave radiation (overall yield of 52-66%). 1H NMR and fluorescence spectroscopy confirmed the complexation event with a calculated association constant of 1.57 × 107 M-1. Likewise, the usefulness of this triple hydrogen bond motif in supramolecular polymerization was demonstrated through viscosity measurements in a crosslinked supramolecular alternating copolymer.

摘要

在此，我们呈现了一种新的、易于功能化的 AAA-DDD 氢键阵列。通过两步合成过程，从 2-氨基烟醛出发，通过微波辐射（总体产率为 52-66%）获得了一种新型的 AAA 单体单元（3a-b）。1H NMR 和荧光光谱证实了这种配合物的形成，其计算的结合常数为 1.57×107 M-1。同样，通过交联超分子交替共聚物中的粘度测量，证明了这种三氢键基序在超分子聚合中的有用性。