Antoniou Athanasios, Harky Amer, Bashir Mohamad, El Khoury Gebrine
Department of Cardiac Surgery, Barts Heart Centre, St Bartholomew's Hospital, London, UK.
School of Medicine, Cardiff University, Cardiff, UK.
Gen Thorac Cardiovasc Surg. 2019 Jan;67(1):20-24. doi: 10.1007/s11748-018-0920-3. Epub 2018 Apr 5.
Aortic valve replacement whether surgical or transcutaneous remains an option for the treatment of severe aortic valve disease; however, current prosthetic devices are associated with complications including, but no limited to, valve thrombosis and thromboembolic events, bleeding events associated with anticoagulation use, prosthetic valve endocarditis and structural valve deterioration. In this effect, aortic valve repair (AVr) has become an attractive alternative in circumventing these potential complications by preservation of the native aortic valve apparatus. In this article, we attempt to present the progress made for AVr over the last two decades. We also wish to highlight the critical steps for successful AVr and the outcome data that demonstrate that can be first-choice treatment in selected patients and finally to emphasize on the key steps for further future development.
主动脉瓣置换术,无论是外科手术还是经皮手术,仍然是治疗严重主动脉瓣疾病的一种选择;然而,目前的人工瓣膜装置存在一些并发症,包括但不限于瓣膜血栓形成和血栓栓塞事件、与抗凝药物使用相关的出血事件、人工瓣膜心内膜炎和人工瓣膜结构退化。因此,主动脉瓣修复术(AVr)通过保留天然主动脉瓣装置,已成为规避这些潜在并发症的一种有吸引力的替代方法。在本文中,我们试图介绍过去二十年来AVr所取得的进展。我们还希望强调成功进行AVr的关键步骤以及表明其在特定患者中可作为首选治疗方法的结果数据,并最终强调未来进一步发展的关键步骤。