生物活性多巴胺油酸衍生物：治疗潜力的综述。
Bioactive Oleic Derivatives of Dopamine: A Review of the Therapeutic Potential.
机构信息
Faculty of Physiotherapy, Opole Medical School, Opole, Poland.
Laboratory of Respiration Physiology, Mossakowski Medical Research Centre PAS, Warsaw, Poland.
出版信息
Adv Exp Med Biol. 2018;1096:73-82. doi: 10.1007/5584_2018_197.
Lipid derivatives of dopamine are a novel class of compounds raising a research interest due to the potential of their being a vehicle for dopamine delivery to the brain. The aim of the present paper is to review the main features of the two most prominent bioactive members of this family, namely, N-oleoyl-dopamine (OLDA) and 3'-O-methyl-N-oleoyl-dopamine (OMe-OLDA), with emphasis on the possible therapeutic properties.
多巴胺的脂质衍生物是一类新型化合物，由于它们有可能成为将多巴胺递送到大脑的载体，因此引起了研究兴趣。本文的目的是综述该家族中两个最突出的生物活性成员，即 N-油酰基多巴胺（OLDA）和 3'-O-甲基-N-油酰基多巴胺（OMe-OLDA）的主要特征，并重点介绍它们可能的治疗特性。
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