Lusink Vanessa, Wong Clare, de Vries Bradley, Ludlow Joanne
Women and Babies Department, Royal Prince Alfred Hospital, Sydney, Australia.
Blacktown Hospital, Sydney, Australia.
Aust N Z J Obstet Gynaecol. 2018 Oct;58(5):590-593. doi: 10.1111/ajo.12808. Epub 2018 Apr 6.
Medical management of miscarriage is an acceptable option available to women, and has advantages of providing timely treatment, while avoiding exposure to surgery and anaesthesia. This retrospective cohort study aimed to determine factors predictive of successful medical management, utilising a single dose protocol of 800 µg vaginal misoprostol. In this cohort, the success rate was 67% (199/296), and smaller mean gestational sac diameter independent of gestational age predicted success (P = 0.046). Success is not significantly related to parity, miscarriage type, pelvic pain or vaginal bleeding at the outset of treatment.
流产的药物治疗是可供女性选择的一种可接受的方式,具有能及时治疗的优点,同时可避免接受手术和麻醉。这项回顾性队列研究旨在确定使用800微克阴道米索前列醇单剂量方案进行药物治疗成功的预测因素。在这个队列中,成功率为67%(199/296),与孕周无关的较小平均孕囊直径可预测治疗成功(P = 0.046)。治疗开始时,成功与否与产次、流产类型、盆腔疼痛或阴道出血无显著关联。