Department of Biostatistics, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Department of Periodontics, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
J Periodontol. 2018 Oct;89(10):1184-1192. doi: 10.1002/JPER.17-0440. Epub 2018 Aug 20.
Anemia as a chronic disease is defined as anemia occurring in chronic infections with inflammatory conditions. The purpose of this study is to assess the association between the number of natural teeth and anemia using nationally representative data.
This study involved a cross-sectional analysis using data from the Korean National Health and Nutrition Examination Survey from 2010 to 2012. A total of 16,875 respondents aged > 19 years without missing values were included in this study. The association between the number of natural teeth and anemia was evaluated by multivariable logistic regression analyses after adjusting for age, sex, body mass index, smoking habits, drinking habits, exercise levels, income levels, education levels, vitamin D levels, diabetes, toothbrushing frequency, energy intake, and percentage of fat in total energy intake among Korean adults.
There was a significant decrease in prevalence of anemia and a significant increase in hemoglobin levels in participants with more natural teeth (P < 0.05). Adjusted odds ratios and their 95% confidence intervals for anemia in participants with numbers of natural teeth of < 15, 15 to 19, 20 to 24, or 24 to 28 were 1 (reference), 0.856(0.591 to 1.24), 0.659(0.5 to 0.868), and 0.607(0.463 to 0.797), respectively, with adjustment for confounding factors (P < 0.05).
The number of natural teeth is negatively associated with anemia in Korean adults, and the number of natural teeth may be considered an independent risk indicator of anemia.
作为一种慢性病,贫血是指在慢性感染伴有炎症的情况下发生的贫血。本研究旨在利用全国代表性数据评估自然牙数与贫血之间的关联。
本研究采用 2010 年至 2012 年韩国国家健康和营养调查的数据进行横断面分析。共纳入 16875 名无缺失值且年龄大于 19 岁的受访者。在调整了年龄、性别、体重指数、吸烟习惯、饮酒习惯、运动水平、收入水平、教育水平、维生素 D 水平、糖尿病、刷牙频率、能量摄入和总能量摄入中脂肪百分比等因素后,采用多变量逻辑回归分析评估自然牙数与贫血之间的关联。
参与者的自然牙数越多,贫血的患病率越低,血红蛋白水平越高(P<0.05)。调整混杂因素后,自然牙数<15、15-19、20-24 或 24-28 颗的参与者发生贫血的调整比值比(OR)及其 95%置信区间(CI)分别为 1(参考)、0.856(0.591-1.24)、0.659(0.5-0.868)和 0.607(0.463-0.797)(P<0.05)。
在韩国成年人中,自然牙数与贫血呈负相关,自然牙数可能被视为贫血的独立危险因素。