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采用横向包皮岛管治疗近端尿道下裂:长期的功能、性和美容结果。

Proximal hypospadias treated with a transverse preputial island tube: long-term functional, sexual, and cosmetic outcomes.

机构信息

University Medical Center (UMC), Utrecht, The Netherlands.

University Children's Hospital UMC Utrecht, Utrecht, The Netherlands.

出版信息

BJU Int. 2018 Sep;122(3):463-471. doi: 10.1111/bju.14234. Epub 2018 May 1.

Abstract

OBJECTIVE

To study long-term urinary and sexual function, and cosmetic outcomes in adult patients who underwent single-stage transverse preputial island tube (TPIT) for proximal hypospadias repair in childhood. Long-term data on outcomes of patients with proximal hypospadias with severe coexisting curvature and insufficient urethral plate are scarce, but are necessary to decide which repair technique is most beneficial.

PATIENTS, SUBJECTS AND METHODS: Patients with proximal hypospadias operated with TPIT (TPIT Group) were compared to patients with distal hypospadias repair (Distal Group) and to a control group of male medical students (Control Group). Participants completed the International Prostate Symptom Score, the International Index of Erectile Function (IIEF-15), additional non-validated questions, and performed uroflowmetry. Cosmesis was assessed in the patients with hypospadias using the Pediatric Penile Perception Score (PPPS); stretched penile length was also measured.

RESULTS

Of the 121 eligible patients with hypospadias, 54 with either TPIT or distal hypospadias repairs participated. The TPIT Group comprised 12 patients (median age of 20.0 years) and the Distal Group comprised 42 patients (median age of 19.6 years). The complication rates were similar, at 8 of the 12 patients in the TPIT Group vs 26/42 (62%) in the Distal Group (P = 0.76). Urinary outcomes were similar in the TPIT, Distal, and the Control (comprised of 148 medical students with a median age of 21.0 years) groups. The TPIT Group had a lower maximum urinary flow rate compared to the Control Group, at 24.1 vs 28.6 mL/s (P < 0.05). IIEF-15 scores were similar in the TPIT, Distal and Control groups, except for 'Orgasmic Function' (7.5 vs 10.0 vs 10.0, respectively; P < 0.01). Although the TPIT Group had a smaller penile length compared to the Distal Group (10.1 vs 12.9 cm, P < 0.01), PPPS outcomes were similar.

CONCLUSION

In these TPIT patients, long-term urinary, sexual and cosmetic outcomes were similar to those in patients with distal hypospadias repairs and controls.

摘要

目的

研究在儿童期行单阶段横形包皮岛状管(TPIT)近端尿道下裂修复术的成年患者的长期尿控和性功能,以及美容效果。对于存在严重伴行弯曲和尿道板不足的近端尿道下裂患者,长期结局数据非常有限,但这是决定哪种修复技术最有益的必要条件。

患者和方法

将接受 TPIT(TPIT 组)治疗的近端尿道下裂患者与接受远端尿道下裂修复术(远端组)的患者和男性医学生对照组(对照组)进行比较。参与者完成国际前列腺症状评分(IPSS)、国际勃起功能指数(IIEF-15)、附加非有效问卷,并进行尿流率测定。采用小儿阴茎知觉评分(PPPS)评估尿道下裂患者的外观;还测量了阴茎伸展长度。

结果

在 121 名符合条件的尿道下裂患者中,54 名患者接受了 TPIT 或远端尿道下裂修复术。TPIT 组有 12 名患者(中位年龄 20.0 岁),远端组有 42 名患者(中位年龄 19.6 岁)。TPIT 组的并发症发生率为 8/12(88%),与远端组的 26/42(62%)相似(P=0.76)。TPIT 组、远端组和对照组(由 148 名中位年龄 21.0 岁的医学生组成)的尿控结局相似。与对照组相比,TPIT 组的最大尿流率较低,分别为 24.1 和 28.6ml/s(P<0.05)。TPIT 组、远端组和对照组的 IIEF-15 评分相似,除“射精功能”外(分别为 7.5、10.0 和 10.0,P<0.01)。尽管 TPIT 组的阴茎长度比远端组小(10.1 和 12.9cm,P<0.01),但 PPPS 结局相似。

结论

在这些接受 TPIT 治疗的患者中,长期尿控、性功能和美容结局与接受远端尿道下裂修复术的患者和对照组相似。

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