Raffoul Jad, Nasir Ammar, Klein Andrew J P
St. Louis University School of Medicine, Saint Louis, MO, USA.
John Cochran Division - Veterans Administration Saint Louis Health Care System, Saint Louis, MO, USA.
Curr Treat Options Cardiovasc Med. 2018 Apr 7;20(5):36. doi: 10.1007/s11936-018-0630-2.
Stent technology has rapidly evolved since the first stainless steel bare metal stents with substantial developments in scaffolding, polymer, drug choice, drug delivery, and elution mechanisms. Most recently, there has been the evolution of bioabsorbable vascular scaffolds, potentially eliminating the need for long-term foreign object retention. These rapid developments have led to an ever-expanding selection of new stents, making the choice of which to use in which patient challenging. Operators must balance potential short- and long-term clinical ramifications, namely stent thrombosis, in-stent restenosis, target lesion revascularization, and target lesion failure. In this review, we hope to provide insight for interventional cardiologists on the details of stent technology and how this impacts outcomes, stent selection, and duration of dual-antiplatelet therapy duration post drug-eluting stent implantation.
自首个不锈钢裸金属支架问世以来，支架技术迅速发展，在支架结构、聚合物、药物选择、药物递送和洗脱机制等方面取得了重大进展。最近，生物可吸收血管支架得到了发展，有可能消除长期留存异物的需求。这些快速发展导致新型支架的选择不断扩大，使得针对不同患者选择合适的支架具有挑战性。操作者必须权衡潜在的短期和长期临床后果，即支架血栓形成、支架内再狭窄、靶病变血管重建和靶病变失败。在本综述中，我们希望为介入心脏病学家提供有关支架技术细节的见解，以及这如何影响治疗结果、支架选择和药物洗脱支架植入后双联抗血小板治疗的持续时间。
