• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

本土医用直线加速器光子束特性及其随入射电子束参数变化的蒙特卡罗研究

Monte Carlo Investigation of Photon Beam Characteristics and its Variation with Incident Electron Beam Parameters for Indigenous Medical Linear Accelerator.

作者信息

Mishra Subhalaxmi, Dixit P K, Selvam T Palani, Yavalkar Sanket S, Deshpande D D

机构信息

Radiological Physics and Advisory Division, Bhabha Atomic Research Centre, Mumbai, India.

Homi Bhabha National Institute, Training School Complex, Anushaktinagar, Mumbai, India.

出版信息

J Med Phys. 2018 Jan-Mar;43(1):1-8. doi: 10.4103/jmp.JMP_125_17.

DOI:10.4103/jmp.JMP_125_17
PMID:29628627
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5879818/
Abstract

PURPOSE

A Monte Carlo model of a 6 MV medical linear accelerator (linac) unit built indigenously was developed using the BEAMnrc user code of the EGSnrc code system. The model was benchmarked against the measurements. Monte Carlo simulations were carried out for different incident electron beam parameters in the study.

MATERIALS AND METHODS

Simulation of indigenously developed linac unit has been carried out using the Monte Carlo based BEAMnrc user-code of the EGSnrc code system. Using the model, percentage depth dose (PDD), and lateral dose profiles were studied using the DOSXYZnrc user code. To identify appropriate electron parameters, three different distributions of electron beam intensity were investigated. For each case, the kinetic energy of the incident electron was varied from 6 to 6.5 MeV (0.1 MeV increment). The calculated dose data were compared against the measurements using the PTW, Germany make RFA dosimetric system (water tank MP3-M and 0.125 cm ion chamber).

RESULTS

The best fit of incident electron beam parameter was found for the combination of beam energy of 6.2 MeV and circular Gaussian distributed source in X and Y with FWHM of 1.0 mm. PDD and beam profiles (along both X and Y directions) were calculated for the field sizes from 5 cm × 5 cm to 25 cm × 25 cm. The dose difference between the calculated and measured PDD and profile values were under 1%, except for the penumbra region where the maximum deviation was found to be around 2%.

CONCLUSIONS

A Monte Carlo model of indigenous linac (6 MV) has been developed and benchmarked against the measured data.

摘要

目的

使用EGSnrc代码系统的BEAMnrc用户代码开发了一个国产6兆伏医用直线加速器（直线加速器）单元的蒙特卡罗模型。该模型与测量结果进行了基准测试。在本研究中，针对不同的入射电子束参数进行了蒙特卡罗模拟。

材料与方法

使用基于蒙特卡罗的EGSnrc代码系统的BEAMnrc用户代码对国产直线加速器单元进行了模拟。使用该模型，通过DOSXYZnrc用户代码研究了百分深度剂量（PDD）和侧向剂量分布。为了确定合适的电子参数，研究了三种不同的电子束强度分布。对于每种情况，入射电子的动能从6兆电子伏变化到6.5兆电子伏（增量为0.1兆电子伏）。使用德国制造的PTW RFA剂量测定系统（水箱MP3 - M和0.125厘米电离室）将计算得到的剂量数据与测量结果进行比较。

结果

对于能量为6.2兆电子伏且在X和Y方向上呈圆形高斯分布、半高宽为1.0毫米的源的组合，发现入射电子束参数的最佳拟合。计算了5厘米×5厘米至25厘米×25厘米射野尺寸的PDD和射野分布（沿X和Y两个方向）。计算值与测量值之间的PDD和分布值的剂量差异在1%以内，但半影区除外，在该区域最大偏差约为2%。

结论

已开发出国产直线加速器（6兆伏）的蒙特卡罗模型，并与测量数据进行了基准测试。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b63/5879818/f5fcfda4465a/JMP-43-1-g015.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b63/5879818/11be3f850b7f/JMP-43-1-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b63/5879818/bb369991f266/JMP-43-1-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b63/5879818/52c37f75eff3/JMP-43-1-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b63/5879818/919c4e3c32cd/JMP-43-1-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b63/5879818/4ce764a659c8/JMP-43-1-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b63/5879818/694b28017909/JMP-43-1-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b63/5879818/22616e99bf0c/JMP-43-1-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b63/5879818/ebd0d92fa627/JMP-43-1-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b63/5879818/6cd6c4097ec2/JMP-43-1-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b63/5879818/ac7c19afea2a/JMP-43-1-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b63/5879818/374d817cb18b/JMP-43-1-g014.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b63/5879818/f5fcfda4465a/JMP-43-1-g015.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b63/5879818/11be3f850b7f/JMP-43-1-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b63/5879818/bb369991f266/JMP-43-1-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b63/5879818/52c37f75eff3/JMP-43-1-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b63/5879818/919c4e3c32cd/JMP-43-1-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b63/5879818/4ce764a659c8/JMP-43-1-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b63/5879818/694b28017909/JMP-43-1-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b63/5879818/22616e99bf0c/JMP-43-1-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b63/5879818/ebd0d92fa627/JMP-43-1-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b63/5879818/6cd6c4097ec2/JMP-43-1-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b63/5879818/ac7c19afea2a/JMP-43-1-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b63/5879818/374d817cb18b/JMP-43-1-g014.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b63/5879818/f5fcfda4465a/JMP-43-1-g015.jpg

相似文献

1
Monte Carlo Investigation of Photon Beam Characteristics and its Variation with Incident Electron Beam Parameters for Indigenous Medical Linear Accelerator.本土医用直线加速器光子束特性及其随入射电子束参数变化的蒙特卡罗研究
J Med Phys. 2018 Jan-Mar;43(1):1-8. doi: 10.4103/jmp.JMP_125_17.
2
Comparison of Measured and Monte Carlo Calculated Dose Distributions from Indigenously Developed 6 MV Flattening Filter Free Medical Linear Accelerator.国产6MV无均整器医用直线加速器测量剂量分布与蒙特卡罗计算剂量分布的比较
J Med Phys. 2018 Jul-Sep;43(3):162-167. doi: 10.4103/jmp.JMP_58_18.
3
Characteristics of elliptical sources in BEAMnrc Monte Carlo system: implementation and application.BEAMnrc蒙特卡罗系统中椭圆源的特性：实现与应用
Med Phys. 2009 Apr;36(4):1046-52. doi: 10.1118/1.3086110.
4
Monte Carlo linear accelerator simulation of megavoltage photon beams: independent determination of initial beam parameters.兆伏级光子束的蒙特卡罗直线加速器模拟：初始束参数的独立确定。
Med Phys. 2012 Jan;39(1):40-7. doi: 10.1118/1.3668315.
5
Monte Carlo study of in-field and out-of-field dose distributions from a linear accelerator operating with and without a flattening-filter.线性加速器在有和没有均整滤过器情况下工作时，射野内和射野外剂量分布的蒙特卡罗研究
Med Phys. 2012 Aug;39(8):5194-203. doi: 10.1118/1.4738963.
6
Determination of initial electron parameters by means of Monte Carlo simulations for the Siemens Artiste Linac 6 MV photon beam.通过蒙特卡罗模拟确定西门子Artiste直线加速器6MV光子束的初始电子参数。
Rep Pract Oncol Radiother. 2019 Jul-Aug;24(4):331-337. doi: 10.1016/j.rpor.2019.05.002. Epub 2019 May 31.
7
Monte carlo electron source model validation for an Elekta Precise linac.蒙特卡罗电子源模型验证用于 Elekta Precise 直线加速器。
Med Phys. 2011 May;38(5):2366-73. doi: 10.1118/1.3570579.
8
Development and evaluation of a GEANT4-based Monte Carlo Model of a 0.35 T MR-guided radiation therapy (MRgRT) linear accelerator.基于 GEANT4 的 0.35 T MR 引导放射治疗（MRgRT）直线加速器的蒙特卡罗模型的开发和评估。
Med Phys. 2021 Apr;48(4):1967-1982. doi: 10.1002/mp.14761. Epub 2021 Mar 4.
9
Experimental verification of EGSnrc Monte Carlo calculated depth doses within a realistic parallel magnetic field in a polystyrene phantom.在聚苯乙烯体模中真实平行磁场下 EGSnrc 蒙特卡罗计算深度剂量的实验验证。
Med Phys. 2017 Sep;44(9):4804-4815. doi: 10.1002/mp.12413. Epub 2017 Jul 17.
10
Monte Carlo simulation of beam characteristics from small fields based on TrueBeam flattening-filter-free mode.基于TrueBeam无均整器模式的小射野射束特性的蒙特卡罗模拟
Radiat Oncol. 2016 Feb 27;11:30. doi: 10.1186/s13014-016-0601-2.

引用本文的文献

1
Sensitivity Analysis of a 6 MeV Photon Beam Monte Carlo Model.6兆电子伏特光子束蒙特卡罗模型的灵敏度分析
J Med Signals Sens. 2023 May 29;13(2):144-152. doi: 10.4103/jmss.jmss_152_21. eCollection 2023 Apr-Jun.
2
Monte Carlo commissioning of radiotherapy LINAC-Introducing an improved methodology.放射治疗直线加速器的蒙特卡罗调试——引入一种改进方法
Rep Pract Oncol Radiother. 2020 Sep-Oct;25(5):720-724. doi: 10.1016/j.rpor.2020.06.009. Epub 2020 Jun 30.
3
Comparison of Measured and Monte Carlo Calculated Dose Distributions from Indigenously Developed 6 MV Flattening Filter Free Medical Linear Accelerator.

本文引用的文献

1
Cobalt, linac, or other: what is the best solution for radiation therapy in developing countries?钴、直线加速器或其他：发展中国家放射治疗的最佳解决方案是什么？
Int J Radiat Oncol Biol Phys. 2014 Jul 1;89(3):476-80. doi: 10.1016/j.ijrobp.2013.12.022.
2
Monte Carlo linear accelerator simulation of megavoltage photon beams: independent determination of initial beam parameters.兆伏级光子束的蒙特卡罗直线加速器模拟：初始束参数的独立确定。
Med Phys. 2012 Jan;39(1):40-7. doi: 10.1118/1.3668315.
3
Inference of the optimal pretarget electron beam parameters in a Monte Carlo virtual linac model through simulated annealing.
国产6MV无均整器医用直线加速器测量剂量分布与蒙特卡罗计算剂量分布的比较
J Med Phys. 2018 Jul-Sep;43(3):162-167. doi: 10.4103/jmp.JMP_58_18.
通过模拟退火在蒙特卡罗虚拟直线加速器模型中推断最优预靶向电子束参数。
Med Phys. 2009 Jun;36(6):2309-19. doi: 10.1118/1.3130102.
4
A comparison between cobalt and linear accelerator-based treatment plans for conformal and intensity-modulated radiotherapy.基于钴和直线加速器的适形放疗及调强放疗治疗计划的比较。
Br J Radiol. 2008 Apr;81(964):304-10. doi: 10.1259/bjr/77023750. Epub 2008 Feb 4.
5
Automatic determination of primary electron beam parameters in Monte Carlo simulation.蒙特卡罗模拟中一次电子束参数的自动测定
Med Phys. 2007 Mar;34(3):1076-84. doi: 10.1118/1.2514155.
6
Back to the future: the history and development of the clinical linear accelerator.回到未来：临床直线加速器的历史与发展
Phys Med Biol. 2006 Jul 7;51(13):R343-62. doi: 10.1088/0031-9155/51/13/R20. Epub 2006 Jun 20.
7
Determination of the initial beam parameters in Monte Carlo linac simulation.蒙特卡罗直线加速器模拟中初始束流参数的确定。
Med Phys. 2006 Apr;33(4):850-8. doi: 10.1118/1.2168433.
8
Monte Carlo calculation of Varian 2300C/D Linac photon beam characteristics: a comparison between MCNP4C, GEANT3 and measurements.瓦里安2300C/D直线加速器光子束特性的蒙特卡罗计算：MCNP4C、GEANT3与测量结果的比较
Appl Radiat Isot. 2005 Mar;62(3):469-77. doi: 10.1016/j.apradiso.2004.07.008.
9
Influence of initial electron beam parameters on Monte Carlo calculated absorbed dose distributions for radiotherapy photon beams.初始电子束参数对蒙特卡罗计算的放射治疗光子束吸收剂量分布的影响。
Med Phys. 2004 Apr;31(4):907-13. doi: 10.1118/1.1668551.
10
Monte Carlo modelling of external radiotherapy photon beams.体外放射治疗光子束的蒙特卡罗模拟
Phys Med Biol. 2003 Nov 7;48(21):R107-64. doi: 10.1088/0031-9155/48/21/r01.