Fujii J, Lytton J, Tada M, MacLennan D H
Banting and Best Department of Medical Research, Charles H. Best Institute, University of Toronto, Canada.
FEBS Lett. 1988 Jan 18;227(1):51-5. doi: 10.1016/0014-5793(88)81412-1.
The nucleotide sequences of cDNAs encoding phospholamban were found to be virtually identical when the cDNA clones were isolated from rabbit slow-twitch (soleus) and rabbit cardiac muscle libraries. These findings demonstrate that both types of muscle express the same phospholamban gene. The deduced amino acid sequences of rabbit and dog phospholamban were identical except for a change from Asp (dog) to Glu (rabbit) at position 2. The nucleotide sequences of the 5'- and the very long 3'-untranslated regions of rabbit and dog phospholamban cDNAs also exhibited a high percentage of identity.
当从兔的慢肌（比目鱼肌）和心肌文库中分离出编码受磷蛋白的cDNA克隆时，发现其核苷酸序列几乎完全相同。这些发现表明，这两种类型的肌肉都表达相同的受磷蛋白基因。兔和犬受磷蛋白的推导氨基酸序列除了第2位氨基酸从犬的天冬氨酸变为兔的谷氨酸外，其余完全相同。兔和犬受磷蛋白cDNA的5'-非翻译区和非常长的3'-非翻译区的核苷酸序列也显示出很高的同源性。
