Obinutuzumab, a potent anti-B-cell agent, for rituximab-unresponsive IgM anti-MAG neuropathy.
作者信息
Rakocevic Goran, Martinez-Outschoorn Ubaldo, Dalakas Marinos C
机构信息
Department of Neurology (G.R., M.C.D.), Department of Hematology (U.M.-O.), Thomas Jefferson University, Philadelphia, PA; and Neuroimmunology Unit (M.C.D.), Department of Pathophysiology, Faculty of Medicine, National and Kapodistrian University of Athens, Greece.
出版信息
Neurol Neuroimmunol Neuroinflamm. 2018 Apr 5;5(4):e460. doi: 10.1212/NXI.0000000000000460. eCollection 2018 Jul.
Abstract
摘要
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Rituximab in anti-MAG neuropathy: More evidence for efficacy and more predictive factors.利妥昔单抗治疗抗MAG神经病变：疗效的更多证据及更多预测因素
J Neurol Sci. 2017 Jun 15;377:224-226. doi: 10.1016/j.jns.2017.04.016. Epub 2017 Apr 13.
2
Ocrelizumab versus Placebo in Primary Progressive Multiple Sclerosis.奥瑞珠单抗与安慰剂治疗原发性进行性多发性硬化症。
N Engl J Med. 2017 Jan 19;376(3):209-220. doi: 10.1056/NEJMoa1606468. Epub 2016 Dec 21.
3
Cytokine-Defined B Cell Responses as Therapeutic Targets in Multiple Sclerosis.细胞因子定义的B细胞反应作为多发性硬化症的治疗靶点
Front Immunol. 2016 Jan 8;6:626. doi: 10.3389/fimmu.2015.00626. eCollection 2015.
4
Long-term efficacy of rituximab in IgM anti-myelin-associated glycoprotein neuropathy: RIMAG follow-up study.利妥昔单抗治疗IgM型抗髓鞘相关糖蛋白神经病的长期疗效：RIMAG随访研究
J Peripher Nerv Syst. 2016 Mar;21(1):10-4. doi: 10.1111/jns.12156.
5
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Ann Neurol. 2009 Mar;65(3):286-93. doi: 10.1002/ana.21577.
6
B cells as therapeutic targets in autoimmune neurological disorders.B细胞作为自身免疫性神经系统疾病的治疗靶点。
Nat Clin Pract Neurol. 2008 Oct;4(10):557-67. doi: 10.1038/ncpneuro0901. Epub 2008 Sep 23.
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Pathogenesis and therapy of neuropathies associated with monoclonal gammopathies.与单克隆丙种球蛋白病相关的神经病变的发病机制与治疗
Ann Neurol. 1995 May;37 Suppl 1:S32-42. doi: 10.1002/ana.410370705.
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