Altmeyer P, Holzmann H, Buhles N, Hör G
Dermatologische Klinik, Ruhr-Universität Bochum.
Hautarzt. 1987 Nov;38(11):664-9.
Bone scintigraphy using 99mTc-EHDP was carried out in 147 psoriatics of both sexes and in 35 nonpsoriatic patients. The psoriatics were subdivided into four groups according to clinical aspects: psoriasis vulgaris (Pv, n = 55), psoriasis inversa (Pinv, n = 32), psoriasis pustulosa of the Königsbeck-Barber type (PpK-B, n = 28), and pustulosis palmaris et plantaris (Ppp, n = 32). The following frequencies of joint involvement were found in the different groups: Pv = 18.3%; Pinv = 22.6%, PpK-B = 11.1%; Ppp = 12.5%; control group 2.3%. In patients suffering from psoriasis vulgaris and psoriasis inversa a pathologic preferential radionuclide uptake was demonstrated in the small peripheral joints of the hands and fingers. The characteristic psoriatic pattern with axial and transverse joint involvement was found in all groups of psoriatic patients. No correlation could be proved between age and pathologic accumulation of the radionuclide or between duration of psoriasis and joint involvement. The so-called anterior chest wall syndrome was found in all patients, but predominantly in those with psoriasis palmaris et plantaris. Finally the indications for bone scintigraphy are discussed.
对147例男女银屑病患者和35例非银屑病患者进行了使用99mTc-EHDP的骨闪烁扫描。根据临床情况,银屑病患者被分为四组:寻常型银屑病(Pv,n = 55)、反向型银屑病(Pinv,n = 32)、Königsbeck-Barber型脓疱型银屑病(PpK-B,n = 28)和掌跖脓疱病(Ppp,n = 32)。在不同组中发现以下关节受累频率:Pv = 18.3%;Pinv = 22.6%,PpK-B = 11.1%;Ppp = 12.5%;对照组为2.3%。在寻常型银屑病和反向型银屑病患者中,手部和手指的小外周关节显示出病理性放射性核素摄取增加。在所有银屑病患者组中均发现了具有轴向和横向关节受累的典型银屑病模式。未证实年龄与放射性核素的病理性积聚之间或银屑病病程与关节受累之间存在相关性。在所有患者中均发现了所谓的前胸壁综合征,但主要见于掌跖脓疱病患者。最后讨论了骨闪烁扫描的适应证。