Palumbo Piergaspare, Usai Sofia, Amatucci Chiara, Pulli Valentina Taurisano, Illuminati Giulio, Vietri Francesco, Tellan Guglielmo
Ann Ital Chir. 2018;89:75-80.
Nausea and vomiting are among the most frequent complications following anesthesia and surgery. Due to anesthesia seems to be primarily responsible for post operative nausea and vomiting (PONV) in Day Surgery facilities, the aim of the study is to evaluate how different methods of anesthesia could modify the onset of postoperative nausea and vomiting in a population of patients undergoing inguinal hernia repair.
Ninehundredten patients, aged between 18 and 87 years, underwent open inguinal hernia repair. The PONV risk has been assessed according to Apfel Score. Local anesthetic infiltration, performed by the surgeon in any cases, has been supported by and analgo-sedation with Remifentanil in 740 patients; Fentanyl was used in 96 cases and the last 74 underwent deep sedation with Propofol .
Among the 910 patients who underwent inguinal hernia repair, PONV occurred in 68 patients (7.5%). Among patients presenting PONV, 29 received Remifentanil, whereas 39 received Fentanyl. In the group of patients receiving Propofol, no one presented PONV. This difference is statistically significant (p < .01). Moreover, only 50 patients of the total sample received antiemetic prophylaxis, and amongst these, PONV occurred in 3 subjects.
Compared to Remifentanil, Fentanyl has a major influence in causing PONV. Nonetheless, an appropriate antiemetic prophylaxis can significantly reduce this undesirable complication. Key words: Day Surgery, Fentanyl, Inguinal, Hernia repair, Nausea, Vomiting.
恶心和呕吐是麻醉和手术后最常见的并发症之一。在日间手术机构中,麻醉似乎是术后恶心呕吐(PONV)的主要原因,本研究旨在评估不同的麻醉方法如何改变接受腹股沟疝修补术患者术后恶心呕吐的发生率。
910例年龄在18至87岁之间的患者接受了开放性腹股沟疝修补术。根据Apfel评分评估PONV风险。在所有病例中均由外科医生进行局部麻醉浸润,并在740例患者中使用瑞芬太尼进行镇痛镇静;96例使用芬太尼,最后74例使用丙泊酚进行深度镇静。
在910例接受腹股沟疝修补术的患者中,68例(7.5%)发生了PONV。在发生PONV的患者中,29例接受了瑞芬太尼,而39例接受了芬太尼。在接受丙泊酚的患者组中,无人发生PONV。这种差异具有统计学意义(p <.01)。此外,在整个样本中只有50例患者接受了预防性止吐治疗,其中3例发生了PONV。
与瑞芬太尼相比,芬太尼在引起PONV方面有更大影响。尽管如此,适当的预防性止吐治疗可以显著减少这种不良并发症。关键词:日间手术;芬太尼;腹股沟;疝修补术;恶心;呕吐