Department of Pathology (A.P.) Obstetrics and Gynecology, Division of Gynecology Oncology (M.H., M.P.S.) Radiology (R.P.C.), University of Miami Miller School of Medicine, Miami, Florida.
Int J Gynecol Pathol. 2019 Jul;38(4):335-339. doi: 10.1097/PGP.0000000000000500.
Wilms tumor (WT) is an uncommon malignant neoplasm that occurs predominantly in the kidney of pediatric patients; its extrarenal counterpart is exceedingly rare. We present the case of an adult female diagnosed with uterine WT. Following hysterectomy due to a uterine mass, histopathologic examination demonstrated a triphasic malignancy composed of epithelial, stromal, and blastemal elements. The characteristic morphologic features, which were supported by immunohistochemical analysis, were diagnostic of WT of the uterus. A summary of the main clinicopathologic parameters, along with a review of all previously reported cases, are described.
威尔姆斯瘤(WT)是一种罕见的恶性肿瘤,主要发生在儿科患者的肾脏中;其肾外对应物极为罕见。我们报告了一例成年女性子宫 WT 的病例。由于子宫肿块行子宫切除术,组织病理学检查显示三时相恶性肿瘤,由上皮、间质和胚细胞瘤组成。特征性的形态学特征,通过免疫组织化学分析得到支持,诊断为子宫 WT。描述了主要临床病理参数的总结,并回顾了所有先前报道的病例。