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经皮肝穿刺胆管造影术

Percutaneous Transhepatic Cholangiography

作者信息

Young Michael, Collier Sara A.

机构信息

Marian University

Oklahoma Dept of Corrections

PMID:29630242
Abstract

Initially reported in 1937, percutaneous transhepatic cholangiography (PTC) is an invasive procedure to visualize and subsequently access the biliary tract (see Percutaneous Transhepatic Cholangiography). PTC involves inserting a needle through the skin, body wall, and liver parenchyma to inject contrast dye directly into the bile ducts. PTC can become important for clinical decision-making or as a precursor to therapy when endoscopic access to the bile ducts is not possible, or other imaging techniques offer inadequate information. PTC provides higher-resolution images of bile duct obstructions, strictures, and leaks than ultrasound, nuclear imaging, computed tomography, and magnetic resonance imaging, including magnetic resonance cholangiopancreatography. After performing PTC, percutaneous interventions of the bile ducts can be attempted, including bile duct stone removal, biopsy, stenting, and drainage. Percutaneous transhepatic biliary drainage (PTBD) was introduced in 1981. For patients with contraindications to bile duct access via endoscopic guidance, such as endoscopic retrograde cholangiopancreatography or choledochoduodenoscopy, PTC and PTBD remain less invasive than surgical access. This activity describes therapies performed in conjunction with PTC to illustrate when PTC is indicated or contraindicated. However, a discussion of these therapies' technical performance and therapeutic outcomes is beyond this topic's scope.

摘要

经皮肝穿刺胆管造影术(PTC)最初于1937年被报道,并在20世纪50年代得到推广,是一种用于诊断和治疗目的的侵入性操作,包括将针插入胆管树,随后放置导管进行经皮肝穿刺胆道引流(PTBD)。将造影剂注入1条或多条胆管(胆管造影),也可能注入十二指肠。PTC可在荧光透视或超声引导下进行(见经皮肝穿刺胆管造影术)。PTC在处理恶性肿瘤引起的梗阻性黄疸方面至关重要,因为它有助于降低胆红素水平、改善肝功能,并使诸如引流和诊断等其他治疗成为可能。在怀疑存在恶性胆管狭窄的病例中,仅依靠影像学进行诊断可能无法得出精确结果,因此需要额外的诊断程序。在经皮胆道置管术(作为PTC的一部分)过程中,通常采用细针穿刺抽吸、刷检细胞学检查和钳取活检。自20世纪80年代以来一直采用的这种方法,仍然是怀疑恶性胆管狭窄诊断工具包中不可或缺的一部分。1981年引入的通过PTC进行的PTBD被认为在引流方面安全有效。这对于无法耐受手术干预的多种合并症患者以及那些无法选择内镜逆行胰胆管造影术(ERCP)的患者尤其有益。然而,它主要侧重于缓解症状而非提供治愈方法。欧洲心血管和介入放射学会(CIRSE)已经制定了PTC的实践指南。