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莱尔米特征

Lhermitte Sign

作者信息

Teoli Dac, Rocha Cabrero Franklyn, Smith Travis, Ghassemzadeh Sassan

机构信息

University of California, Riverside

Harbor UCLA Medical Center

Abstract

Lhermitte's sign (also known as Lhermitte's phenomenon or the barber chair phenomenon) is the term used that describes a transient sensation of an electric shock that extends down the spine and extremities upon flexion and/or movement of the neck. It was first described by Marie and Chatelin in 1917, but was erroneously first credited to Babinski and Dubois, and thenafter credited to Jean Jaque Lhermitte through the seminal paper  (1924) by Lhermitte et al. and Gutre. Lhermitte described this phenomenon in patients with multiple sclerosis and other spinal cord diseases. It was then further hypothesized that it resulted from irritation and inflammation of the spinal cord, likely in the posterior and lateral columns. Lhermitte's sign is also classified as one of the paroxysmal pain syndromes of multiple sclerosis, a chronic, predominantly immune-mediated disease of the central nervous system. It is among the most common causes of neurological disability in young adults globally. It can cause many other neurological clinical symptoms, including mononuclear painful visual loss, spinal cord hemiparesis, mono/paraparesis, hypoesthesia, dysesthesia, paraesthesia, urinary and/or sphincter dysfunction, diplopia, oscillopsia, vertigo, gait ataxia, dysmetria, intentional/postural tremor, facial paresis, faciobrachial–crural hemiparesis, and faciobrachial–crural hemihypesthesia. Lhermitte's sign should not be confused with the Uhthoff phenomenon, another finding in multiple sclerosis patients that is defined by heat sensitivity after prolonged heat exposure, saunas, and hot tubs.

摘要

莱尔米特征(也称为莱尔米特现象或理发椅现象)是一个术语,用于描述在颈部屈曲和/或移动时,一种电击样的短暂感觉沿脊柱和四肢向下延伸。它于1917年由玛丽和沙泰兰首次描述,但最初错误地归功于巴宾斯基和迪布瓦,后来通过莱尔米特等人和居特雷于1924年发表的开创性论文归功于让·雅克·莱尔米特。莱尔米特在患有多发性硬化症和其他脊髓疾病的患者中描述了这种现象。随后进一步推测,它是由脊髓,可能是后柱和侧柱的刺激和炎症引起的。莱尔米特征也被归类为多发性硬化症的阵发性疼痛综合征之一,多发性硬化症是一种慢性的、主要由免疫介导的中枢神经系统疾病。它是全球年轻人神经功能障碍最常见的原因之一。它会引起许多其他神经临床症状,包括单核细胞性疼痛性视力丧失、脊髓偏瘫、单瘫/截瘫、感觉减退、感觉异常、感觉异常、排尿和/或括约肌功能障碍、复视、视振荡、眩晕、步态共济失调、辨距不良、意向性/姿势性震颤、面瘫、面臂-小腿偏瘫和面臂-小腿偏身感觉减退。莱尔米特征不应与Uhthoff现象相混淆,Uhthoff现象是多发性硬化症患者的另一个表现,定义为长时间受热、洗桑拿和泡热水澡后对热敏感。

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