肾血管性高血压的全身血流动力学：经皮腔内血管成形术血管重建后的变化。
Systemic haemodynamics in renovascular hypertension: changes after revascularization with percutaneous transluminal angioplasty.
作者信息
Valvo E, Bedogna V, Gammaro L, Taddei G, Maso R, Cavaggioni M, Tonon M, Maschio G
机构信息
Divisione di Nefrologia, Ospedale di Verona, Italy.
出版信息
J Hypertens. 1987 Oct;5(5):629-32. doi: 10.1097/00004872-198710000-00019.
The systemic haemodynamic pattern and its changes after at least 6 months of successful percutaneous transluminal angioplasty (PTRA) was evaluated in a group of patients with renovascular hypertension (RVH). Fourteen patients, nine males and five females, aged 21 to 58 years, were studied; 12 had fibrodysplastic and two had atherosclerotic stenosing renal vascular lesions. Seven were cured and seven improved. Hypertension was characterized by increased plasma volume (PV) and total peripheral vascular resistance (TPR). Mean peripheral plasma renin activity (PRA) and 24-h urine aldosterone (UA) were elevated. However, the vasoconstriction did not appear to be related to the increased activity of the renin-angiotensin system. After at least 6 months of a successful PTRA, the fall in blood pressure (BP) was associated with a decrease in TPR; PV appeared normal, and PRA and UA became normal.
对一组肾血管性高血压（RVH）患者进行了评估，观察成功实施经皮腔内血管成形术（PTRA）至少6个月后的全身血流动力学模式及其变化。研究对象为14例患者，其中男性9例，女性5例，年龄在21至58岁之间；12例患有纤维肌发育异常，2例患有动脉粥样硬化性狭窄性肾血管病变。7例治愈，7例病情改善。高血压的特征为血浆容量（PV）增加和总外周血管阻力（TPR）增加。平均外周血浆肾素活性（PRA）和24小时尿醛固酮（UA）升高。然而，血管收缩似乎与肾素-血管紧张素系统活性增加无关。成功实施PTRA至少6个月后，血压（BP）下降与TPR降低相关；PV似乎正常，PRA和UA也恢复正常。
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