Pediatric Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Pediatric Hematology & Oncology, Children's Hospital Colorado, Anschutz Medical Campus, Aurora, Colorado.
Pediatr Blood Cancer. 2018 Jul;65(7):e27054. doi: 10.1002/pbc.27054. Epub 2018 Apr 6.
Histiocytic sarcoma is an extremely rare tumor in children. It may occur sporadically or in association with other hematological malignancies. It arises most commonly in the lymph nodes but may occur anywhere in the body and clinical presentation is usually with advanced disease. Following tissue diagnosis and staging, management is with chemotherapy though there are no standard regimes. Surgery has been used successfully for local control. This is the first description of the use of peritonectomy and hyperthermic intraperitoneal chemotherapy to treat histiocytic sarcoma. The 4-year-old patient has been disease free for 6 years.
组织细胞肉瘤是一种极为罕见的儿童肿瘤。它可能是散发性的，也可能与其他血液系统恶性肿瘤相关。它最常发生在淋巴结，但也可能发生在身体的任何部位，临床表现通常为晚期疾病。在进行组织诊断和分期后，通常采用化疗进行治疗，但目前尚无标准方案。手术已成功用于局部控制。这是首例使用腹膜切除术和腹腔内热化疗治疗组织细胞肉瘤的描述。该 4 岁患者已无疾病 6 年。
